Histone H2A/H2B/H3 (IPR007125)

Short name: Histone_H2A/H2B/H3

Overlapping homologous superfamilies

Domain relationships



Five major families of histones exist: H1/H5, H2A, H2B, H3, and H4 [PMID: 16472024] Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. The core histones together with some other DNA binding proteins form a superfamily defined by a common fold and distant sequence similarities [PMID: 7651829, PMID: 9016552]. Some proteins contain local homology domains related to the histone fold [PMID: 9305837].

This entry represents a domain found in histones H2A, H2B and H3.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0000786 nucleosome

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.