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Crystal structure of X. tropicalis Spred1 EVH-1 domain

X-ray diffraction
1.15Å resolution
PDB entry 1xod coloured by chain, front view.
PDB entry 1xod coloured by chain, side view.
PDB entry 1xod coloured by chain, top view.
Source organism: Xenopus tropicalis
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Sprouty-related, EVH1 domain-containing protein 1
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Multimeric state: monomeric
Accessible surface area: 5962.86 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-179281
Assembly 2 (preferred)
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Assembly Name: Sprouty-related, EVH1 domain-containing protein 1
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Multimeric state: monomeric
Accessible surface area: 6849.12 Å2
Buried surface area: 170.0 Å2
Dissociation area: 85 Å2
Dissociation energy (ΔGdiss): -0.18 kcal/mol
Dissociation entropy (TΔSdiss): 0.86 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-179281

Macromolecules

Sprouty-related, EVH1 domain-containing protein 1
Chains: A, B
Length: 118 amino acids
Theoretical weight: 12.97 KDa
Source organism: Xenopus tropicalis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q66JG9 (Residues: 8-123; Coverage: 29%)
Gene name: spred1
Pfam: WH1 domain
InterPro:
CATH: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
SCOP: Enabled/VASP homology 1 domain (EVH1 domain)
Sprouty-related, EVH1 domain-containing protein 1 in PDB entry 1xod, assembly 2, front view.
Sprouty-related, EVH1 domain-containing protein 1 in PDB entry 1xod, assembly 2, side view.
Sprouty-related, EVH1 domain-containing protein 1 in PDB entry 1xod, assembly 2, top view.
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