Structure analysis

Human pepsin 3A in complex with a phosphonate inhibitor IVA-VAL-VAL-LEU(P)-(O)PHE-ALA-ALA-OME

X-ray diffraction
1.96Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-143585

Macromolecules

Chain: E
Length: 326 amino acids
Theoretical weight: 34.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P0DJD7 (Residues: 63-388; Coverage: 87%)
Gene name: PGA4
Pfam: Eukaryotic aspartyl protease
InterPro:
CATH: Acid Proteases
SCOP: Pepsin-like

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