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STRUCTURE OF IMMUNOGLOBULIN

X-ray diffraction
3.2Å resolution
PDB entry 1igy coloured by chain, front view.
PDB entry 1igy coloured by chain, side view.
PDB entry 1igy coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-heavy chain and IG-light kappa chain
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Multimeric state: hetero tetramer
Accessible surface area: 61422.35 Å2
Buried surface area: 16036.53 Å2
Dissociation area: 1,785.93 Å2
Dissociation energy (ΔGdiss): 13.74 kcal/mol
Dissociation entropy (TΔSdiss): 14.21 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-134700

Macromolecules

Immunoglobulin kappa constant
Chains: A, C
Length: 213 amino acids
Theoretical weight: 23.52 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Immunoglobulin kappa constant in PDB entry 1igy, assembly 1, front view.
Immunoglobulin kappa constant in PDB entry 1igy, assembly 1, side view.
Immunoglobulin kappa constant in PDB entry 1igy, assembly 1, top view.
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Ig gamma-1 chain C region, membrane-bound form
Chains: B, D
Length: 434 amino acids
Theoretical weight: 47.91 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01869 (Residues: 1-320; Coverage: 81%)
Gene names: Igh-4, Ighg1
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Ig gamma-1 chain C region, membrane-bound form in PDB entry 1igy, assembly 1, front view.
Ig gamma-1 chain C region, membrane-bound form in PDB entry 1igy, assembly 1, side view.
Ig gamma-1 chain C region, membrane-bound form in PDB entry 1igy, assembly 1, top view.
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