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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B

Source organisms:
Biochemical function: not assigned
Biological process: cell adhesion
Cellular component: viral envelope

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00516
Domain description: Envelope glycoprotein GP120
Occurring in:
  1. Surface protein gp120
The deposited structure of PDB entry 1g9m contains 1 copy of Pfam domain PF00516 (Envelope glycoprotein GP120) in Surface protein gp120. Showing 1 copy in chain A [auth G].

PF05790
Domain description: Immunoglobulin C2-set domain
Occurring in:
  1. T-cell surface glycoprotein CD4
The deposited structure of PDB entry 1g9m contains 1 copy of Pfam domain PF05790 (Immunoglobulin C2-set domain) in T-cell surface glycoprotein CD4. Showing 1 copy in chain B [auth C].

PF00047
Domain description: Immunoglobulin domain
Occurring in:
  1. T-cell surface glycoprotein CD4
The deposited structure of PDB entry 1g9m contains 1 copy of Pfam domain PF00047 (Immunoglobulin domain) in T-cell surface glycoprotein CD4. Showing 1 copy in chain B [auth C].

InterPro InterPro annotations
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. ANTIBODY 17B, HEAVY CHAIN
  2. ANTIBODY 17B, LIGHT CHAIN
IPR000777
Domain description: Human immunodeficiency virus 1, envelope glycoprotein Gp120
Occurring in:
  1. Surface protein gp120
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. ANTIBODY 17B, HEAVY CHAIN
  2. ANTIBODY 17B, LIGHT CHAIN
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR036377
Domain description: Gp120 core superfamily
Occurring in:
  1. Surface protein gp120
IPR008424
Domain description: Immunoglobulin C2-set
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR013151
Domain description: Immunoglobulin-like beta-sandwich domain
Occurring in:
  1. T-cell surface glycoprotein CD4

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
The deposited structure of PDB entry 1g9m contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in T-cell surface glycoprotein CD4. Showing 2 copies in chain B [auth C].
The deposited structure of PDB entry 1g9m contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in ANTIBODY 17B, LIGHT CHAIN. Showing 2 copies in chain C [auth L].
The deposited structure of PDB entry 1g9m contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in ANTIBODY 17B, HEAVY CHAIN. Showing 2 copies in chain D [auth H].
2.170.40.20
Class: Mainly Beta
Architecture: Beta Complex
Topology: HIV Envelope Protein Gp120; Chain G
Homology: Human immunodeficiency virus 1, Gp160, envelope glycoprotein
Occurring in:
  1. Surface protein gp120
The deposited structure of PDB entry 1g9m contains 1 copy of CATH domain 2.170.40.20 (HIV Envelope Protein Gp120; Chain G) in Surface protein gp120. Showing 1 copy in chain A [auth G].
SCOP SCOP annotations
48727
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. T-cell surface glycoprotein CD4
  2. ANTIBODY 17B, HEAVY CHAIN
  3. ANTIBODY 17B, LIGHT CHAIN
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in T-cell surface glycoprotein CD4. Showing 1 copy in chain B [auth C].
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in ANTIBODY 17B, LIGHT CHAIN. Showing 1 copy in chain C [auth L].
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 48727 (V set domains (antibody variable domain-like)) in ANTIBODY 17B, HEAVY CHAIN. Showing 1 copy in chain D [auth H].
48942
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. ANTIBODY 17B, HEAVY CHAIN
  2. ANTIBODY 17B, LIGHT CHAIN
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in ANTIBODY 17B, LIGHT CHAIN. Showing 1 copy in chain C [auth L].
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in ANTIBODY 17B, HEAVY CHAIN. Showing 1 copy in chain D [auth H].
56503
Class: Alpha and beta proteins (a+b)
Fold: gp120 core
Superfamily: gp120 core
Occurring in:
  1. Surface protein gp120
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 56503 (gp120 core) in Surface protein gp120. Showing 1 copy in chain A [auth G].
49142
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. T-cell surface glycoprotein CD4
The deposited structure of PDB entry 1g9m contains 1 copy of SCOP domain 49142 (C2 set domains) in T-cell surface glycoprotein CD4. Showing 1 copy in chain B [auth C].

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