› › Structure analysis

HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B

X-ray diffraction
2.2Å resolution
PDB entry 1g9m coloured by chain, front view.
PDB entry 1g9m coloured by chain, side view.
PDB entry 1g9m coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 4 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero tetramer
Accessible surface area: 43114.59 Å2
Buried surface area: 11544.89 Å2
Dissociation area: 1,208.27 Å2
Dissociation energy (ΔGdiss): -2.68 kcal/mol
Dissociation entropy (TΔSdiss): 13.44 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-224967

Macromolecules

Surface protein gp120
Chain: G
Length: 321 amino acids
Theoretical weight: 35.43 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P04578 (Residues: 83-492; Coverage: 39%)
Gene name: env
Pfam: Envelope glycoprotein GP120
InterPro:
CATH: Human immunodeficiency virus 1, Gp160, envelope glycoprotein
SCOP: gp120 core
Surface protein gp120 in PDB entry 1g9m, assembly 1, front view.
Surface protein gp120 in PDB entry 1g9m, assembly 1, side view.
Surface protein gp120 in PDB entry 1g9m, assembly 1, top view.
Molecule details ›

Search similar proteins

T-cell surface glycoprotein CD4
Chain: C
Length: 185 amino acids
Theoretical weight: 20.5 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01730 (Residues: 26-210; Coverage: 43%)
Gene name: CD4
Pfam:
InterPro:
CATH: Immunoglobulins
SCOP:
T-cell surface glycoprotein CD4 in PDB entry 1g9m, assembly 1, front view.
T-cell surface glycoprotein CD4 in PDB entry 1g9m, assembly 1, side view.
T-cell surface glycoprotein CD4 in PDB entry 1g9m, assembly 1, top view.
Molecule details ›

Search similar proteins

ANTIBODY 17B, LIGHT CHAIN
Chain: L
Length: 214 amino acids
Theoretical weight: 23.44 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
InterPro:
CATH: Immunoglobulins
SCOP:
ANTIBODY 17B, LIGHT CHAIN in PDB entry 1g9m, assembly 1, front view.
ANTIBODY 17B, LIGHT CHAIN in PDB entry 1g9m, assembly 1, side view.
ANTIBODY 17B, LIGHT CHAIN in PDB entry 1g9m, assembly 1, top view.
Molecule details ›

Search similar proteins

ANTIBODY 17B, HEAVY CHAIN
Chain: H
Length: 229 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
InterPro:
CATH: Immunoglobulins
SCOP:
ANTIBODY 17B, HEAVY CHAIN in PDB entry 1g9m, assembly 1, front view.
ANTIBODY 17B, HEAVY CHAIN in PDB entry 1g9m, assembly 1, side view.
ANTIBODY 17B, HEAVY CHAIN in PDB entry 1g9m, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links