Function and Biology

X-RAY CRYSTAL STRUCTURE OF THE HUMAN GALECTIN-3 CARBOHYDRATE RECOGNITION DOMAIN (CRD) AT 2.1 ANGSTROM RESOLUTION

Source organism: Homo sapiens
Biochemical function: carbohydrate binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00337
Domain description: Galactoside-binding lectin
Occurring in:
  1. Galectin-3
The deposited structure of PDB entry 1a3k contains 1 copy of Pfam domain PF00337 (Galactoside-binding lectin) in Galectin-3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001079
Domain description: Galectin, carbohydrate recognition domain
Occurring in:
  1. Galectin-3
IPR044156
Domain description: Galectin-like
Occurring in:
  1. Galectin-3
IPR013320
Domain description: Concanavalin A-like lectin/glucanase domain superfamily
Occurring in:
  1. Galectin-3

Structure domain

CATH CATH domain
2.60.120.200
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Galectin-3
The deposited structure of PDB entry 1a3k contains 1 copy of CATH domain 2.60.120.200 (Jelly Rolls) in Galectin-3. Showing 1 copy in chain A.
SCOP SCOP annotation
49932
Class: All beta proteins
Fold: Concanavalin A-like lectins/glucanases
Superfamily: Concanavalin A-like lectins/glucanases
Occurring in:
  1. Galectin-3
The deposited structure of PDB entry 1a3k contains 1 copy of SCOP domain 49932 (Galectin (animal S-lectin)) in Galectin-3. Showing 1 copy in chain A.