PDBe 1e96

X-ray diffraction
2.4Å resolution

Structure of the Rac/p67phox complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related C3 botulinum toxin substrate 1 Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: NEW P63000 (Residues: 2-192; Coverage: 100%)
Gene names: MIG5, RAC1, TC25
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Neutrophil cytosol factor 2 Chain: B
Molecule details ›
Chain: B
Length: 203 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: NEW P19878 (Residues: 1-203; Coverage: 39%)
Gene names: NCF2, NOXA2, P67PHOX
Sequence domains: Tetratricopeptide repeat
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX7.2
Spacegroup: P3221
Unit cell:
a: 83.22Å b: 83.22Å c: 138.53Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.248 0.244 0.284
Expression system: Escherichia coli BL21