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Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF07686
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig-like domain-containing protein
The deposited structure of PDB entry 3e3q contains 8 copies of Pfam domain PF07686 (Immunoglobulin V-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain G [auth C].

PF00129
Domain description: Class I Histocompatibility antigen, domains alpha 1 and 2
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain
The deposited structure of PDB entry 3e3q contains 8 copies of Pfam domain PF00129 (Class I Histocompatibility antigen, domains alpha 1 and 2) in H-2 class I histocompatibility antigen, L-D alpha chain. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
IPR001039
Domain description: MHC class I alpha chain, alpha1 alpha2 domains
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
IPR011162
Domain description: MHC classes I/II-like antigen recognition protein
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain
IPR011161
Domain description: MHC class I-like antigen recognition-like
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain
IPR037055
Domain description: MHC class I-like antigen recognition-like superfamily
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Ig-like domain-containing protein
  2. TCR beta chain
The deposited structure of PDB entry 3e3q contains 8 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Ig-like domain-containing protein. Showing 1 copy in chain G [auth C].
The deposited structure of PDB entry 3e3q contains 8 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in TCR beta chain. Showing 1 copy in chain D [auth E].
3.30.500.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1
Homology: MHC class I-like antigen recognition-like
Occurring in:
  1. H-2 class I histocompatibility antigen, L-D alpha chain
The deposited structure of PDB entry 3e3q contains 8 copies of CATH domain 3.30.500.10 (Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1) in H-2 class I histocompatibility antigen, L-D alpha chain. Showing 1 copy in chain A.

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