› 2z1p

X-ray diffraction
2.5Å resolution

The Enterococcus faecalis MSCRAMM ACE binds its ligands by the collagen Hug Model

Released:
DOI: 10.2210/pdb2z1p/pdb
PDB entry 2z1p coloured by chain, front view.
PDB entry 2z1p coloured by chain, side view.
PDB entry 2z1p coloured by chain, top view.
Source organism: Enterococcus faecalis
Primary publication:
The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model.
Liu Q, Ponnuraj K, Xu Y, Ganesh VK, Sillanpää J, Murray BE, Narayana SV, Höök M
J Biol Chem 282 19629-37 (2007)
PMID: 17392280

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182829 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gram-positive cocci surface proteins LPxTG domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 39.32 KDa
Source organism: Enterococcus faecalis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q836L2 (Residues: 32-367; Coverage: 50%)
Gene name: EF_1099
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P3121
Unit cell:
a: 80.239Å b: 80.239Å c: 105.91Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.23 0.266
Expression system: Escherichia coli

Quick links

Citations

11 review citations

The rise of the Enterococcus: beyond vancomycin resistance.
Arias et al. (2012)
10 more

8 mentions without citation

Structural biology of Gram-positive bacterial adhesins.
Vengadesan et al. (2011)
7 more