Function and Biology

EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS AT 1.85 A RESOLUTION

Source organism: Candida albicans
Biochemical function: cell adhesion molecule binding
Biological process: cell wall organization
Cellular component: extracellular vesicle

EC 3.2.1.58: Glucan 1,3-beta-glucosidase

Reaction catalysed:
Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose
Systematic name:
3-beta-D-glucan glucohydrolase
Alternative Name(s):
  • 1,3-beta-glucan glucohydrolase
  • Beta-1,3-glucan exo-hydrolase
  • Exo (1->3)-beta-glucanase
  • Exo-1,3-beta-D-glucanase
  • Exo-1,3-beta-glucanase
  • Exo-1,3-beta-glucosidase
  • Exo-beta-(1->3)-D-glucanase
  • Exo-beta-(1->3)-glucanohydrolase
  • Exo-beta-1,3-D-glucanase
  • Exo-beta-1,3-glucanase

Sequence family

Pfam Protein family (Pfam)
PF00150
Domain description: Cellulase (glycosyl hydrolase family 5)
Occurring in:
  1. Glucan 1,3-beta-glucosidase
The deposited structure of PDB entry 1cz1 contains 1 copy of Pfam domain PF00150 (Cellulase (glycosyl hydrolase family 5)) in Glucan 1,3-beta-glucosidase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR018087
Domain description: Glycoside hydrolase, family 5, conserved site
Occurring in:
  1. Glucan 1,3-beta-glucosidase
IPR001547
Domain description: Glycoside hydrolase, family 5
Occurring in:
  1. Glucan 1,3-beta-glucosidase
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Glucan 1,3-beta-glucosidase

Structure domain

CATH CATH domain
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Glucan 1,3-beta-glucosidase
The deposited structure of PDB entry 1cz1 contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Glucan 1,3-beta-glucosidase. Showing 1 copy in chain A.
SCOP SCOP annotation
51487
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Occurring in:
  1. Glucan 1,3-beta-glucosidase
The deposited structure of PDB entry 1cz1 contains 1 copy of SCOP domain 51487 (beta-glycanases) in Glucan 1,3-beta-glucosidase. Showing 1 copy in chain A.