› 1wmz

X-ray diffraction
1.7Å resolution

Crystal Structure of C-type Lectin CEL-I complexed with N-acetyl-D-galactosamine

Released:
DOI: 10.2210/pdb1wmz/pdb
PDB entry 1wmz coloured by chain, front view.
PDB entry 1wmz coloured by chain, side view.
PDB entry 1wmz coloured by chain, top view.
Source organism: Cucumaria echinata
Primary publication:
Characteristic recognition of N-acetylgalactosamine by an invertebrate C-type Lectin, CEL-I, revealed by X-ray crystallographic analysis.
Sugawara H, Kusunoki M, Kurisu G, Fujimoto T, Aoyagi H, Hatakeyama T
J Biol Chem 279 45219-25 (2004)
PMID: 15319425

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-181699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 140 amino acids
Theoretical weight: 16.05 KDa
Source organism: Cucumaria echinata
UniProt:
  • Canonical: Q7M462 (Residues: 1-140; Coverage: 100%)
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

3 bound ligands:
Ligand NGA 3 x NGA
Ligand CA 12 x CA
Ligand A2G 1 x A2G
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 39.58Å b: 52.24Å c: 136.59Å
α: 90° β: 91.66° γ: 90°
R-values:
R R work R free
0.16 0.158 0.186

Quick links

Citations

1 review citation

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
10 other articles

8 mentions without citation

Functional Diversity of Novel Lectins with Unique Structural Features in Marine Animals.
Hatakeyama et al. (2023)
7 more