All Arrow Environments > arrow env id: 393741

SMARTS

[#8]=[#6](-[#6,#1])-[#8&-:23].[#1:22]-[#8]-[#6,#1]

Arrow Environment Type: 0_3_ezm1

Arrow Environment seen in 163 catalytic steps

m-csa:550 - 2-dehydro-3-deoxy-phosphogluconate aldolase - mechanism: 1 - step: 1
m-csa:170 - peptidyl-dipeptidase A - mechanism: 1 - step: 1
m-csa:39 - inosine-uridine preferring nucleoside hydrolase - mechanism: 1 - step: 1
m-csa:710 - cytosine deaminase (bacterial) - mechanism: 1 - step: 1
m-csa:343 - methylglutaconyl-CoA hydratase - mechanism: 1 - step: 1
m-csa:175 - HIV-1 retropepsin - mechanism: 1 - step: 1
m-csa:510 - 8-oxoguanine DNA-glycosylase (ExoA family) - mechanism: 1 - step: 1
m-csa:167 - bacterial leucyl aminopeptidase - mechanism: 1 - step: 1
m-csa:636 - cytosine deaminase (yeast) - mechanism: 1 - step: 1
m-csa:644 - limonene-1,2-epoxide hydrolase - mechanism: 1 - step: 1
m-csa:212 - nitrogenase - mechanism: 1 - step: 1
m-csa:179 - chaperonin ATPase - mechanism: 1 - step: 1
m-csa:833 - DNA helicase - mechanism: 1 - step: 1
m-csa:803 - aldehyde dehydrogenase (NAD+) (class 2) - mechanism: 1 - step: 1
m-csa:732 - dCTP deaminase - mechanism: 1 - step: 1
m-csa:844 - dUTP diphosphatase - mechanism: 1 - step: 1
m-csa:1005 - Phenylethanolamine N-methyltransferase - mechanism: 1 - step: 1
m-csa:524 - histone acetyltransferase (GCN5 family) - mechanism: 1 - step: 1
m-csa:561 - cellulase (GH45) - mechanism: 1 - step: 1
m-csa:917 - methionyl aminopeptidase - mechanism: 1 - step: 1
m-csa:823 - ADP-ribose diphosphatase - mechanism: 1 - step: 1
m-csa:996 - Peptidoglycan-N-acetylglucosamine deacetylase Bc1960 - mechanism: 1 - step: 1
m-csa:595 - scytalidopepsin B - mechanism: 1 - step: 1
m-csa:105 - aldehyde dehydrogenase (FAD-independent) - mechanism: 1 - step: 1
m-csa:626 - bontoxilysin - mechanism: 1 - step: 1
m-csa:19 - mannosyl-oligosaccharide 1,2-alpha-mannosidase - mechanism: 1 - step: 1
m-csa:98 - peptide deformylase - mechanism: 1 - step: 1
m-csa:706 - D-Ala-D-Ala dipeptidase - mechanism: 1 - step: 1
m-csa:171 - carboxypeptidase A - mechanism: 1 - step: 1
m-csa:97 - cytidine deaminase - mechanism: 1 - step: 1
m-csa:546 - fructose-bisphosphatase - mechanism: 1 - step: 1
m-csa:168 - membrane dipeptidase - mechanism: 1 - step: 1
m-csa:591 - stromelysin 1 - mechanism: 1 - step: 1
m-csa:641 - anthrax lethal factor endopeptidase - mechanism: 1 - step: 1
m-csa:559 - cellulase (GH9) - mechanism: 1 - step: 1
m-csa:516 - carbonate dehydratase (gamma class) - mechanism: 1 - step: 1
m-csa:148 - transaldolase (type I) - mechanism: 1 - step: 1
m-csa:488 - L-rhamnose isomerase - mechanism: 1 - step: 1
m-csa:1001 - Prolidase (Xaa-Pro dipeptidase) - mechanism: 1 - step: 1
m-csa:657 - mitochondrial processing peptidase - mechanism: 1 - step: 1
m-csa:993 - Glutathione S-transferase A - mechanism: 1 - step: 1
m-csa:315 - enoyl-CoA hydratase - mechanism: 1 - step: 1
m-csa:642 - vesicle-fusing ATPase - mechanism: 1 - step: 1
m-csa:165 - micrococcal nuclease - mechanism: 1 - step: 1
m-csa:182 - methylisocitrate lyase - mechanism: 1 - step: 1
m-csa:27 - phospholipase C - mechanism: 1 - step: 1
m-csa:517 - carbonate dehydratase (beta class) - mechanism: 1 - step: 1
m-csa:836 - exodeoxyribonuclease (lambda-induced) - mechanism: 1 - step: 2
m-csa:658 - arabinogalactan endo-1,4-beta-galactosidase - mechanism: 1 - step: 2
m-csa:548 - endo-1,4-beta-xylanase (glycosyl hydrolase 10) - mechanism: 1 - step: 2
m-csa:827 - fructan beta-fructosidase - mechanism: 1 - step: 2
m-csa:774 - lysozyme (glycosyl hydrolase 25 family) - mechanism: 1 - step: 2
m-csa:19 - mannosyl-oligosaccharide 1,2-alpha-mannosidase - mechanism: 1 - step: 2
m-csa:831 - glucan 1,3-beta-glucosidase - mechanism: 1 - step: 2
m-csa:817 - chitinase (GH18, class II) - mechanism: 1 - step: 2
m-csa:203 - lysozyme (glycosyl hydrolase 22 family) - mechanism: 1 - step: 2
m-csa:741 - histidinol dehydrogenase - mechanism: 1 - step: 2
m-csa:36 - (S)-2-haloacid dehalogenase - mechanism: 1 - step: 2
m-csa:916 - inorganic diphosphatase - mechanism: 1 - step: 2
m-csa:325 - isochorismate synthase (menaquinone-specific) - mechanism: 1 - step: 2
m-csa:835 - exo-alpha-sialidase (GH33 Family) - mechanism: 1 - step: 2
m-csa:616 - hyaluronoglucosaminidase - mechanism: 1 - step: 2
m-csa:812 - 5'-nucleotidase (mitochondrial) - mechanism: 1 - step: 2
m-csa:347 - feruloyl CoA hydratase/lyase - mechanism: 1 - step: 2
m-csa:727 - phosphoserine phosphatase - mechanism: 1 - step: 2
m-csa:285 - oligo-1,6-glucosidase - mechanism: 1 - step: 2
m-csa:819 - chitinase C - mechanism: 1 - step: 2
m-csa:560 - cellulase (GH12) - mechanism: 1 - step: 2
m-csa:141 - 4-cresol dehydrogenase (hydroxylating) - mechanism: 1 - step: 2
m-csa:793 - mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase - mechanism: 1 - step: 2
m-csa:976 - α‑glucosidase maltase-glucoamylase - mechanism: 1 - step: 2
m-csa:667 - alpha-N-arabinofuranosidase - mechanism: 1 - step: 2
m-csa:828 - exo-alpha-sialidase (GH34 Family) - mechanism: 1 - step: 2
m-csa:308 - xylose isomerase (actinobacterial) - mechanism: 1 - step: 2
m-csa:47 - protein-tyrosine-phosphatase non-receptor class - mechanism: 1 - step: 2
m-csa:947 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ - mechanism: 1 - step: 3
m-csa:671 - N-carbamoyl-D-amino-acid hydrolase - mechanism: 1 - step: 3
m-csa:529 - phospholipase A2 (group group IVA) - mechanism: 1 - step: 3
m-csa:781 - UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase - mechanism: 1 - step: 3
m-csa:716 - nicotinamidase - mechanism: 1 - step: 3
m-csa:25 - N-carbamoylsarcosine amidase - mechanism: 1 - step: 3
m-csa:810 - fructose-2,6-bisphosphate 2-phosphatase - mechanism: 1 - step: 3
m-csa:31 - thymidylate synthase - mechanism: 1 - step: 3
m-csa:681 - pectinesterase - mechanism: 1 - step: 3
m-csa:711 - glyceraldehyde-3-phosphate dehydrogenase (NADP+) - mechanism: 1 - step: 3
m-csa:488 - L-rhamnose isomerase - mechanism: 1 - step: 3
m-csa:345 - 3-hydroxyisobutyryl-CoA hydrolase - mechanism: 1 - step: 3
m-csa:532 - secondary-alcohol dehydrogenase (coenzyme-F420) - mechanism: 1 - step: 3
m-csa:764 - glucosylceramidase - mechanism: 1 - step: 3
m-csa:690 - dextranase - mechanism: 1 - step: 3
m-csa:42 - nuclease - mechanism: 1 - step: 3
m-csa:166 - leukotriene-A4 hydrolase - mechanism: 1 - step: 3
m-csa:100 - betaine-aldehyde dehydrogenase - mechanism: 1 - step: 3
m-csa:52 - fructose-bisphosphate aldolase (Class II) - mechanism: 1 - step: 3
m-csa:967 - NADPH-dependent 7-cyano-7-deazaguanine reductase - mechanism: 1 - step: 3
m-csa:829 - endo-alpha-sialidase - mechanism: 1 - step: 3
m-csa:1005 - Phenylethanolamine N-methyltransferase - mechanism: 1 - step: 3
m-csa:228 - dTDP-glucose 4,6-dehydratase - mechanism: 1 - step: 4
m-csa:2 - beta-lactamase (Class A) - mechanism: 1 - step: 4
m-csa:580 - glucan endo-1,3-beta-D-glucosidase - mechanism: 1 - step: 4
m-csa:93 - hydroxymethylglutaryl-CoA reductase (NADPH) - mechanism: 1 - step: 4
m-csa:157 - hydroxyacylglutathione hydrolase - mechanism: 1 - step: 4
m-csa:793 - mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase - mechanism: 1 - step: 4
m-csa:803 - aldehyde dehydrogenase (NAD+) (class 2) - mechanism: 1 - step: 4
m-csa:59 - 3-dehydroquinate synthase - mechanism: 1 - step: 4
m-csa:190 - isopentenyl-diphosphate delta-isomerase (type 1) - mechanism: 1 - step: 4
m-csa:807 - adenine DNA glycosylase - mechanism: 1 - step: 4
m-csa:92 - UDP-glucose 6-dehydrogenase - mechanism: 1 - step: 4
m-csa:550 - 2-dehydro-3-deoxy-phosphogluconate aldolase - mechanism: 1 - step: 4
m-csa:159 - aryldialkylphosphatase - mechanism: 1 - step: 4
m-csa:49 - histidine decarboxylase - mechanism: 1 - step: 5
m-csa:31 - thymidylate synthase - mechanism: 1 - step: 5
m-csa:254 - squalene-hopene cyclase - mechanism: 1 - step: 6
m-csa:550 - 2-dehydro-3-deoxy-phosphogluconate aldolase - mechanism: 1 - step: 6
m-csa:103 - vanillyl-alcohol oxidase - mechanism: 1 - step: 6
m-csa:222 - fructose-bisphosphate aldolase (Class I) - mechanism: 1 - step: 6
m-csa:636 - cytosine deaminase (yeast) - mechanism: 1 - step: 6
m-csa:162 - deoxyribonuclease (pyrimidine dimer) - mechanism: 1 - step: 6
m-csa:34 - catechol 2,3-dioxygenase - mechanism: 1 - step: 7
m-csa:148 - transaldolase (type I) - mechanism: 1 - step: 7
m-csa:222 - fructose-bisphosphate aldolase (Class I) - mechanism: 1 - step: 8
m-csa:700 - deoxycytidylate 5-hydroxymethyltransferase - mechanism: 1 - step: 8
m-csa:488 - L-rhamnose isomerase - mechanism: 2 - step: 1
m-csa:732 - dCTP deaminase - mechanism: 2 - step: 1
m-csa:455 - asparaginase - mechanism: 2 - step: 1
m-csa:821 - omptin - mechanism: 2 - step: 1
m-csa:829 - endo-alpha-sialidase - mechanism: 2 - step: 1
m-csa:2 - beta-lactamase (Class A) - mechanism: 2 - step: 1
m-csa:163 - ribonuclease HI - mechanism: 2 - step: 1
m-csa:148 - transaldolase (type I) - mechanism: 2 - step: 1
m-csa:71 - uridine nucleosidase (family I) - mechanism: 2 - step: 1
m-csa:182 - methylisocitrate lyase - mechanism: 2 - step: 1
m-csa:993 - Glutathione S-transferase A - mechanism: 2 - step: 1
m-csa:92 - UDP-glucose 6-dehydrogenase - mechanism: 2 - step: 1
m-csa:836 - exodeoxyribonuclease (lambda-induced) - mechanism: 2 - step: 1
m-csa:396 - aspartic peptidase - mechanism: 2 - step: 1
m-csa:686 - diisopropyl-fluorophosphatase - mechanism: 2 - step: 2
m-csa:774 - lysozyme (glycosyl hydrolase 25 family) - mechanism: 2 - step: 2
m-csa:359 - lactoglutathione lyase - mechanism: 2 - step: 2
m-csa:899 - beta-N-acetylhexosaminidase - mechanism: 2 - step: 2
m-csa:546 - fructose-bisphosphatase - mechanism: 2 - step: 2
m-csa:383 - tryptophan synthase - mechanism: 2 - step: 2
m-csa:397 - alpha-amylase - mechanism: 2 - step: 2
m-csa:989 - Retroviral integrase - mechanism: 2 - step: 2
m-csa:166 - leukotriene-A4 hydrolase - mechanism: 2 - step: 2
m-csa:203 - lysozyme (glycosyl hydrolase 22 family) - mechanism: 2 - step: 2
m-csa:488 - L-rhamnose isomerase - mechanism: 2 - step: 3
m-csa:148 - transaldolase (type I) - mechanism: 2 - step: 4
m-csa:92 - UDP-glucose 6-dehydrogenase - mechanism: 2 - step: 4
m-csa:99 - methanol dehydrogenase (cytochrome c) - mechanism: 2 - step: 4
m-csa:2 - beta-lactamase (Class A) - mechanism: 2 - step: 4
m-csa:107 - aerobic carbon monoxide dehydrogenase - mechanism: 2 - step: 4
m-csa:13 - amine dehydrogenase - mechanism: 2 - step: 5
m-csa:254 - squalene-hopene cyclase - mechanism: 2 - step: 5
m-csa:228 - dTDP-glucose 4,6-dehydratase - mechanism: 2 - step: 5
m-csa:254 - squalene-hopene cyclase - mechanism: 2 - step: 6
m-csa:148 - transaldolase (type I) - mechanism: 2 - step: 7
m-csa:829 - endo-alpha-sialidase - mechanism: 3 - step: 1
m-csa:686 - diisopropyl-fluorophosphatase - mechanism: 3 - step: 1
m-csa:152 - holo-[acyl-carrier-protein] synthase - mechanism: 3 - step: 1
m-csa:107 - aerobic carbon monoxide dehydrogenase - mechanism: 3 - step: 2
m-csa:93 - hydroxymethylglutaryl-CoA reductase (NADPH) - mechanism: 3 - step: 4
m-csa:534 - myosin ATPase - mechanism: 6 - step: 1