› 6ih3

X-ray diffraction
1.94Å resolution

Crystal structure of Phosphite Dehydrogenase from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide

Released:
DOI: 10.2210/pdb6ih3/pdb
PDB entry 6ih3 coloured by chain, front view.
PDB entry 6ih3 coloured by chain, side view.
PDB entry 6ih3 coloured by chain, top view.
Source organism: Ralstonia sp. 4506
Primary publication:
Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Liu Y, Feng Y, Wang L, Guo X, Liu W, Li Q, Wang X, Xue S, Zhao Z
ACS Catalysis 9 1883-1887 (2019)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124464 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphite dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 336 amino acids
Theoretical weight: 36.63 KDa
Source organism: Ralstonia sp. 4506
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: G4XDR8 (Residues: 1-336; Coverage: 100%)
Gene name: ptxD
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand A7R 1 x A7R
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P21212
Unit cell:
a: 97.77Å b: 122.584Å c: 61.662Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.167 0.202
Expression system: Escherichia coli BL21(DE3)

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