D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)

Short name: D-isomer_2_OHA_DH_cat_dom

Overlapping homologous superfamilies

Domain relationships



A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. The catalytic domain contains a number of conserved charged residues which may play a role in the catalytic mechanism [PMID: 9126843]. The NAD-binding domain is described in IPR006140

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0051287 NAD binding
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.