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Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain in complex with galactose

Source organism: Paracoccus sp. 32d
Biochemical function: hydrolase activity, acting on glycosyl bonds
Biological process: carbohydrate metabolic process
Cellular component: not assigned

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EC 3.2.1.23: Beta-galactosidase

Reaction catalysed:
Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides
Systematic name:
Beta-D-galactoside galactohydrolase
Alternative Name(s):
  • Beta-D-galactanase
  • Beta-D-lactosidase
  • Beta-lactosidase
  • Exo-(1->4)-beta-D-galactanase
  • Hydrolact
  • Lactase
  • Lactozym
  • Maxilact
  • Oryzatym
  • S 2107
  • Sumiklat
  • Trilactase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF18565
Domain description: Glycoside hydrolase family 2 C-terminal domain 5
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF18565 (Glycoside hydrolase family 2 C-terminal domain 5) in Beta-D-galactosidase. Showing 1 copy in chain A.
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF18565 (Glycoside hydrolase family 2 C-terminal domain 5) in Beta-D-galactosidase. Showing 1 copy in chain B.

PF02836
Domain description: Glycosyl hydrolases family 2, TIM barrel domain
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF02836 (Glycosyl hydrolases family 2, TIM barrel domain) in Beta-D-galactosidase. Showing 1 copy in chain A.
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF02836 (Glycosyl hydrolases family 2, TIM barrel domain) in Beta-D-galactosidase. Showing 1 copy in chain B.

PF00703
Domain description: Glycosyl hydrolases family 2
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF00703 (Glycosyl hydrolases family 2) in Beta-D-galactosidase. Showing 1 copy in chain A.
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF00703 (Glycosyl hydrolases family 2) in Beta-D-galactosidase. Showing 1 copy in chain B.

PF02837
Domain description: Glycosyl hydrolases family 2, sugar binding domain
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF02837 (Glycosyl hydrolases family 2, sugar binding domain) in Beta-D-galactosidase. Showing 1 copy in chain A.
The deposited structure of PDB entry 5ldr contains 1 copy of Pfam domain PF02837 (Glycosyl hydrolases family 2, sugar binding domain) in Beta-D-galactosidase. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR006101
Domain description: Glycoside hydrolase, family 2
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR040605
Domain description: Glycoside hydrolase family 2, domain 5
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR023232
Domain description: Glycoside hydrolase, family 2, active site
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR023230
Domain description: Glycoside hydrolase, family 2, conserved site
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR006103
Domain description: Glycoside hydrolase family 2, catalytic domain
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR006102
Domain description: Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR036156
Domain description: Beta-Galactosidase/glucuronidase domain superfamily
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR006104
Domain description: Glycosyl hydrolases family 2, sugar binding domain
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase
IPR008979
Domain description: Galactose-binding-like domain superfamily
Occurring in:
  1. Beta-D-galactosidase
  2. Beta-D-galactosidase

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