Assemblies
Assembly Name:
Beta-secretase 1
Multimeric state:
homo dimer
Accessible surface area:
32666.34 Å2
Buried surface area:
839.64 Å2
Dissociation area:
176.45
Å2
Dissociation energy (ΔGdiss):
-14.24
kcal/mol
Dissociation entropy (TΔSdiss):
13.34
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157562
Assembly Name:
Beta-secretase 1
Multimeric state:
homo dimer
Accessible surface area:
32666.34 Å2
Buried surface area:
839.64 Å2
Dissociation area:
176.45
Å2
Dissociation energy (ΔGdiss):
-14.24
kcal/mol
Dissociation entropy (TΔSdiss):
13.34
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157562
Assembly Name:
Beta-secretase 1
Multimeric state:
homo dimer
Accessible surface area:
32666.34 Å2
Buried surface area:
839.64 Å2
Dissociation area:
176.45
Å2
Dissociation energy (ΔGdiss):
-14.24
kcal/mol
Dissociation entropy (TΔSdiss):
13.34
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157562
Macromolecules
Chains: A, B
Length: 395 amino acids
Theoretical weight: 44.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Eukaryotic aspartyl protease
InterPro:
Length: 395 amino acids
Theoretical weight: 44.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P56817 (Residues: 53-447; Coverage: 82%)
Pfam: Eukaryotic aspartyl protease
InterPro:
- Aspartic peptidase domain superfamily
- Aspartic peptidase A1 family
- Memapsin-like
- Peptidase family A1 domain
- Aspartic peptidase, active site
- Beta-secretase BACE1
- Beta-secretase BACE
