X-ray diffraction
1.65Å resolution

Crystal Structure of Ad37 fiber knob in complex with GD1a oligosaccharide


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-179159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Adenoviral fibre protein knob domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 194 amino acids
Theoretical weight: 21.72 KDa
Source organism: Human adenovirus D37
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q64823 (Residues: 177-365; Coverage: 52%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL, NGA, SIA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 60.99Å b: 69.77Å c: 74.9Å
α: 90° β: 94.92° γ: 90°
R R work R free
0.16 0.16 0.187
Expression system: Escherichia coli BL21(DE3)