Assemblies
Assembly Name:
Protease
Multimeric state:
hetero dimer
Accessible surface area:
43838.32 Å2
Buried surface area:
6071.25 Å2
Dissociation area:
2,740.05
Å2
Dissociation energy (ΔGdiss):
22.1
kcal/mol
Dissociation entropy (TΔSdiss):
15.01
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-138005
Macromolecules
Chain: A
Length: 563 amino acids
Theoretical weight: 64.85 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
Length: 563 amino acids
Theoretical weight: 64.85 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04585 (Residues: 588-1147; Coverage: 39%)
Pfam:
- Reverse transcriptase (RNA-dependent DNA polymerase)
- Reverse transcriptase thumb domain
- Reverse transcriptase connection domain
- RNase H
- DNA/RNA polymerase superfamily
- Reverse transcriptase domain
- Reverse transcriptase/Diguanylate cyclase domain
- Reverse transcriptase thumb
- Reverse transcriptase connection
- Ribonuclease H-like superfamily
- Ribonuclease H superfamily
- Ribonuclease H domain
Chain: B
Length: 447 amino acids
Theoretical weight: 52.24 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
Length: 447 amino acids
Theoretical weight: 52.24 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04585 (Residues: 588-1015; Coverage: 30%)
Pfam:
- Reverse transcriptase (RNA-dependent DNA polymerase)
- Reverse transcriptase thumb domain
- Reverse transcriptase connection domain
- DNA/RNA polymerase superfamily
- Reverse transcriptase domain
- Reverse transcriptase/Diguanylate cyclase domain
- Reverse transcriptase thumb
- Reverse transcriptase connection