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PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT

X-ray diffraction
2.5Å resolution
PDB entry 2isd coloured by chain, front view.
PDB entry 2isd coloured by chain, side view.
PDB entry 2isd coloured by chain, top view.
Source organism: Rattus norvegicus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
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Multimeric state: monomeric
Accessible surface area: 22342.42 Å2
Buried surface area: 217.47 Å2
Dissociation area: 108.74 Å2
Dissociation energy (ΔGdiss): 2.07 kcal/mol
Dissociation entropy (TΔSdiss): -0.34 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-145423
Assembly 2
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Assembly Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
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Multimeric state: monomeric
Accessible surface area: 25031.31 Å2
Buried surface area: 217.85 Å2
Dissociation area: 108.92 Å2
Dissociation energy (ΔGdiss): 1.94 kcal/mol
Dissociation entropy (TΔSdiss): -0.33 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-145423

Macromolecules

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Chains: A, B
Length: 624 amino acids
Theoretical weight: 70.57 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10688 (Residues: 133-756; Coverage: 83%)
Gene name: Plcd1
Pfam:
InterPro:
CATH:
SCOP:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 in PDB entry 2isd, assembly 1, front view.
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 in PDB entry 2isd, assembly 1, side view.
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 in PDB entry 2isd, assembly 1, top view.
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