Function and Biology

FitAB bound to DNA

Source organism: Neisseria gonorrhoeae
Biochemical function: protein binding
Biological process: migration in host
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF22513
Domain description: Antitoxin FitA-like, ribbon-helix-helix
Occurring in:
  1. Antitoxin FitA

PF01850
Domain description: PIN domain
Occurring in:
  1. Toxin FitB
The deposited structure of PDB entry 2bsq contains 4 copies of Pfam domain PF01850 (PIN domain) in Toxin FitB. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013321
Domain description: Arc-type ribbon-helix-helix
Occurring in:
  1. Antitoxin FitA
IPR010985
Domain description: Ribbon-helix-helix
Occurring in:
  1. Antitoxin FitA
IPR022907
Domain description: VapC family
Occurring in:
  1. Toxin FitB
IPR002716
Domain description: PIN domain
Occurring in:
  1. Toxin FitB
IPR029060
Domain description: PIN-like domain superfamily
Occurring in:
  1. Toxin FitB

Structure domains

CATH CATH domains
1.10.1220.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant
Homology: Met repressor-like
Occurring in:
  1. Antitoxin FitA
The deposited structure of PDB entry 2bsq contains 4 copies of CATH domain 1.10.1220.10 (Arc Repressor Mutant) in Antitoxin FitA. Showing 1 copy in chain E.
3.40.50.1010
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: 5'-nuclease
Occurring in:
  1. Toxin FitB
The deposited structure of PDB entry 2bsq contains 4 copies of CATH domain 3.40.50.1010 (Rossmann fold) in Toxin FitB. Showing 1 copy in chain A.
SCOP SCOP annotations
140550
Class: All alpha proteins
Fold: Ribbon-helix-helix
Superfamily: Ribbon-helix-helix
Occurring in:
  1. Antitoxin FitA
The deposited structure of PDB entry 2bsq contains 4 copies of SCOP domain 140550 (Trafficking protein A-like) in Antitoxin FitA. Showing 1 copy in chain E.
89619
Class: Alpha and beta proteins (a/b)
Fold: PIN domain-like
Superfamily: PIN domain-like
Occurring in:
  1. Toxin FitB
The deposited structure of PDB entry 2bsq contains 4 copies of SCOP domain 89619 (PIN domain) in Toxin FitB. Showing 1 copy in chain A.