Function and Biology Details
Reaction catalysed:
Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- HhH-GPD domain
- Adenine DNA glycosylase, C-terminal
- NUDIX hydrolase-like domain superfamily
- Endonuclease III-like, iron-sulphur cluster loop motif
- Helix-hairpin-helix motif
- Helix-hairpin-helix, base-excision DNA repair, C-terminal
- A/G-specific adenine glycosylase MutY
- Adenine/Thymine-DNA glycosylase
1 more domain
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Adenine DNA glycosylase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-120478 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):