Publications describing MEROPS

The most comprehensive literature resource that is built around the MEROPS classification is the Handbook of Proteolytic Enzymes (Rawlings, N.D. & Salvesen, G.S., eds), Elsevier, 2013.

The full list of relevant publications is:

  1. Rawlings, N.D. & Barrett, A.J. (1993) Evolutionary families of peptidases. Biochem J 290, 205-218.  PubMed

  2. Rawlings, N.D. & Barrett, A.J. (1994) Families of serine peptidases. Methods Enzymol 244, 19-61.  PubMed

  3. Rawlings, N.D. & Barrett, A.J. (1994) Families of cysteine peptidases. Methods Enzymol 244, 461-486.  PubMed

  4. Rawlings, N.D. & Barrett, A.J. (1995) Families of aspartic peptidases, and those of unknown catalytic mechanism. Methods Enzymol 248, 105-120.  PubMed

  5. Rawlings, N.D. & Barrett, A.J. (1995) Evolutionary families of metallopeptidases. Methods Enzymol 248, 183-228.  PubMed

  6. Barrett, A.J. & Rawlings, N.D. (1995) Families and clans of serine peptidases. Arch Biochem Biophys 318, 247-250.  PubMed

  7. Barrett, A.J. & Rawlings, N.D. (1996) Families and clans of cysteine peptidases. Perspect Drug Discov Design 6, 1-11.

  8. Rawlings, N.D. & Barrett, A.J. (1997) Classification of peptidases by comparisons of primary and secondary structures. In: Proteolysis in Cell Functions (Eds Hopsu-Havu,V.K.; Järvinen,M.; Kirschke,H), pp. 13-21, IOS Press, Amsterdam.

  9. Barrett, A.J., Rawlings, N.D. & Woessner, J.F. (eds) (1998) Handbook of Proteolytic Enzymes, Academic Press, London.

  10. Chen, J.-M., Rawlings, N. D. & Barrett, A. J. (1998) Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases.FEBS Lett 441, 361-365.  PubMed

  11. Rawlings, N.D. & Barrett, A.J. (1999) MEROPS: the peptidase database. Nucleic Acids Res 27, 325-331.  PubMed

  12. Rawlings, N.D. & Barrett, A.J. (2000) MEROPS: the peptidase database. Nucleic Acids Res 28, 323-325.  PubMed

  13. Barrett, A.J. & Rawlings, N.D. (2001) Evolutionary lines of cysteine peptidases. Biol Chem 382, 727-733.  PubMed

  14. Barrett, A.J., Rawlings, N.D. & O'Brien, E. A. (2001) The MEROPS database as a protease information system. J Struct Biol 134, 95-102.  PubMed

  15. Rawlings, N.D., O'Brien, E.A. & Barrett, A.J. (2002) MEROPS: the protease database. Nucleic Acids Res 30, 343-346.  PubMed

  16. Studholme, D.J., Rawlings, N.D., Barrett, A.J. & Bateman, A. (2003) A comparison of Pfam and MEROPS: two databases, one comprehensive, and one specialised BMC Bioinformatics 4, 17.  PubMed

  17. Rawlings, N.D., Tolle, D.P. & Barrett, A.J. (2004) MEROPS: the peptidase database. Nucleic Acids Res. 32 Database issue, D160-D164.  PubMed

  18. Barrett, A.J., Rawlings, N.D. & Woessner, J.F. (eds) (2004) Handbook of Proteolytic Enzymes, 2nd edition, Academic Press, London.

  19. Barrett, A.J. (2004) Bioinformatics of proteases in the MEROPS database. Curr Opin Drug Discov Devel 7, 334-341.  PubMed

  20. Rawlings, N.D., Tolle, D.P. & Barrett, A.J. (2004) Evolutionary families of peptidase inhibitors. Biochem J 378, 705-716.  PubMed

  21. Rawlings, N.D., Morton, F.R. & Barrett, A.J. (2006) MEROPS: the peptidase database Nucleic Acids Res. 34 Database issue, D270-D272.  PubMed

  22. Barrett, A.J. & Rawlings, N.D. (2007) 'Species' of peptidases Biol. Chem. 388, 1151-1157.  PubMed

  23. Rawlings, N.D., Morton, F.R., Kok, C.Y., Kong, J. & Barrett, A.J. (2008) MEROPS: the peptidase database Nucleic Acids Res. 36 Database issue, D320-D325.  PubMed

  24. Rawlings, N.D. & Morton, F.R. (2008) The MEROPS batch BLAST: A tool to detect peptidases and their non-peptidase homologues in a genome Biochimie 90, 243-59.  PubMed

  25. Rawlings, N.D. (2009) A large and accurate collection of peptidase cleavages in the MEROPS database Database (Oxford) 2009, bap015.  PubMed.

  26. Rawlings, N.D., Barrett, A.J. & Bateman, A. (2010) MEROPS: the peptidase database Nucleic Acids Res. 38, D227-33.  PubMed

  27. Rawlings, N.D. (2010) Peptidase inhibitors in the MEROPS database Biochimie 92, 1463-83.  PubMed

  28. Rawlings, N.D., Barrett, A.J. & Bateman, A. (2011) Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes J Biol Chem. 286, 38321-8.  PubMed

  29. Rawlings, N.D., Barrett, A.J. & Bateman, A. (2012) MEROPS: the database of proteolytic enzymes, their substrates and inhibitors Nucleic Acids Res. 40 Database issue, D343-50.  PubMed

  30. Rawlings, N.D. & Salvesen, G. S. (eds) (2013) Handbook of Proteolytic Enzymes, 3rd edition, Elsevier, Amsterdam.

  31. Rawlings, N.D. (2013) Identification and prioritization of novel uncharacterized peptidases for biochemical characterization Database (Oxford) 2013, bat022.  PubMed

  32. Rawlings, N.D., Waller, M., Barrett, A.J. & Bateman, A. (2014) MEROPS: the database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res. 42 Database issue, D503-9.  PubMed

  33. Rawlings, N.D., Barrett, A.J. & Bateman, A. (2014) Using the MEROPS Database for Proteolytic Enzymes and Their Inhibitors and Substrates. Curr. Protoc. Bioinform. 48:1.25.1-1.25.33.  PubMed

  34. Rawlings, N.D., Barrett, A.J. & Finn, R.D. (2016) Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res 44 Database issue, D343-D350.  PubMed

  35. Rawlings, N.D. (2016) Peptidase specificity from the substrate cleavage collection in the MEROPS database and a tool to measure cleavage site conservation. Biochimie 122, 5-30.  PubMed

  36. Rawlings, N.D. (2017) Using the MEROPS Database for Investigation of Lysosomal Peptidases, Their Inhibitors, and Substrates. Methods Mol Biol. 1594, 213-226.  PubMed

  37. Rawlings, N.D., Barrett, A.J., Thomas, P.D., Huang, X., Bateman, A. & Finn, R.D. (2018) The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database. Nucleic Acids Res 46 Database issue, D624-D632.  PubMed

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