Non-Human Primates

Welcome to the KIR-NHP database, a specialist database for the Killer-cell Immunoglobulin-like Receptors of Non-Human Primates. The database includes currently chimpanzee, orangutan and rhesus macaque KIR sequences, and is subject to quality control. Incorporated in the database are currently known and annotated KIR sequences. For macaque KIR currently only full-length sequences are accepted for annotation.

Nomenclature

For allele designation the database uses the 2010 nomenclature rules described by the WHO Nomenclature Committee for Factors of the HLA System.

The alignments used have been curated by:

For macaque species:

  • Natasja de Groot, Nel Otting and Ronald Bontrop
    Biomedical Primate Research Centre
    Lange Kleiweg 161 RIJSWIJK, The Netherlands
    Tel: +31 15 284 2500
    Email: ipdmhc.nhp@bprc.nl
    URL: http://www.bprc.nl/

For all other non-human primate species:

  • Libby Guethlein
    Department of Structural Biology and of Microbiology and Immunology
    Stanford University School of Medicine
    Stanford, United States of America
    Tel:
    Email: libbyg@stanford.edu

Tools

Alleles per species

Roll over the graph to view the number of alleles per species

References

Please cite the IPD-NHKIR database whenever you publish your sequences. When citing the database you can use the following articles.

  • Robinson J, Guethlein LA, Maccari G, Blokhuis J, Bimber BN, de Groot NG, Sanderson ND, Abi-Rached L, Walter L, Bontrop RE, Hammond JA, Marsh SGE, Parham P. Nomenclature for the KIR of non-human species Immunogenetics. 2018 Jun 4, doi: 10.1007/s00251-018-1064-4.

Group curator

Dr. Natasja de Groot - degroot [at] bprc.nl

Biomedical Primate Research Centre, Department of Comparitive Genetics and Refinement, The Netherlands

Organisms

Below a list of organisms belonging to the Non-Human Primates group. If you are working on non-human KIR nomenclature and your species is not represented, please contact the IPD Support.