Canids

It is essential to have a consistent and universal nomenclature for MHC alleles, and to facilitate this, a Canine MHC Nomenclature Committee has been established under the auspices of the International Society for Animal Genetics (ISAG). This committee reviews all nucleotide sequences as they are produced and assigns appropriate allele names.

Alleles

List all Canids alleles

Species

Species belonging to the Canids group

Align

Multi locus inter- and intra- species alignment

Nomenclature

New nomenclature is used where possible, and tables of previous equivalents are given. Accession numbers and references for published sequences are listed.

DLA-DRB1

161

Class II

DLA-88

139

Class I

DLA-DQB1

79

Class II

DLA-DQA1

30

Class II

DLA-12

17

Class I

DLA-DRB1

13

Class II

DLA-64

9

Class I

DLA-79

8

Class I

DLA-DQB1

7

Class II

DLA-DRB1

7

Class II

Above are listed the most populated genes within the Canids group. To list all the genes within the DLA taxonomic group, please visit the species page.

Search DLA alleles

Group curator

Dr. Lorna Kennedy - Lorna.Kennedy [at] manchester.ac.uk

University of Manchester, Centre for Integrated Genomic Medical Research, United Kingdom

References

  • Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, De Groot NG, Flicek P, Bontrop RE, Hammond JA and Marsh SGE IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Res. (2017), 45: D860–D864
  • Kennedy LJ, Altet L, Angles JM, Barnes A, Carter SD, Francino O, Gerlach, JA, Happ GM, Ollier WER, Polvi A, Thomson W, Wagner Nomenclature for factors of the Dog Major Histocompatibility System (DLA), 1998: First report of the ISAG DLA Nomenclature Committee Tissue Antigens (1999) 54:312-21 Animal Genetics (2000) 31:52-61 full text
  • Kennedy LJ, Altet L, Angles JM, Barnes A, Carter SD, Francino O, Gerlach, JA, Happ GM, Ollier WER, Thomson W, Wagner Nomenclature for the DLA system, 2000. Second report of the ISAG DLA Nomenclature Committee Tissue Antigens (2001) 58:55-70 Animal Genetics (2001) 32:193-199 full text