Polymorphism Search Tool Help
This tool allows the user to retrieve data on HLA sequence polymorphism. The output displays polymorphism found at different positions within the HLA sequences.
Search Level - Enter either the locus or a more specific allele group. For example, "A" will search all HLA-A alleles where as "A*01" will only analyse the HLA sequences beginning "A*01".
Codon - Select the region of interest, you can view polymorphism across the entire sequence or enter a specific codon position. The codon positions use the numbering from the IPD-IMGT/HLA protein alignments. To view the entire sequence leave the "Codon" box blank.
Omit - The final option allows you to omit the monomorphic positions detected, i.e. those codons that display no polymorphism. This reduces the size of the output produced.