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Cellular Phenotype Database
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Phenotypes browsing
Ontology terms browsing
About the Project
Gene
Reagent ID
Gene attribute
Phenotype
Study
Fruit Fly
Homo sapiens
Ontology terms
Any study terms
BZH_SH4-mCherry-GFP
CellMorph
CGSR DNA damage
EMBL-secretion screen
GFP-RNF168
JCB Metazoan actinome
Mitocheck
NF-kB oscillation screen
PP2A-B55α
Phagokinetic track
(
?
)
Search by «Ontology term» provides results for ontology terms through the studies having common genes knocked down.
Search by «Any study term» provides results for phenotype terms through the studies having common genes knocked down.
Search by study acronim provides results for phenotype terms observed
together
for a given reagent/gene
e.g.
AURKC
or
ENSG00000105146
e.g.
124936
CMPO off:
e.g. kinesin complex
e.g. plasma membrane
Phenotypes — original study terms — browsing
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ontology tree
Browse phenotypes or, by clicking on ✎
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link by the phenotype term, choose multiple phenotypes set from different studies or from the same study to retrieve a list of gene/reagent pairs showing all selected phenotypes
Please chose here Phenotypes by clicking on them
Phenotype original term:
Screen:
Phenotypes by Study and Screen type
Screen type
BZH_SH4-mCherry-GFP
(B1_SyM_1)
Primary
1.
Intracellular retention of SH4(HASPB)-GFP
✎
collect
2.
Intracellular retention of SH4(YES)-mCherry
✎
collect
BZH_SH4-mCherry-GFP
(B1_SyM_2)
Validation
1.
Intracellular retention of SH4(HASPB)-GFP
✎
collect
2.
Intracellular retention of SH4(YES)-mCherry
✎
collect
CGSR DNA damage
(C2_SyM_1)
Primary
1.
Reduction in IR-induced 53BP1 foci in HeLa cells
✎
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CGSR DNA damage
(C2_SyM_2)
Primary
1.
Reduction in IR-induced 53BP1 foci in U2OS cells
✎
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CellMorph
(C1_SyM_1)
Primary
1.
Actin fiber cells
✎
collect
2.
BL phenotype (decrease in the number of cells and increase of metaphase cells)
✎
collect
3.
Big cells
✎
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4.
Bright nuclei
✎
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5.
Cells with protrusions
✎
collect
6.
Elongated cells with protrusions
✎
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7.
Elongated cells
✎
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8.
High actin ratio cells
✎
collect
9.
Lamellipodia + high actin ratio cells
✎
collect
10.
Lamellipodia cells
✎
collect
11.
Large cells
✎
collect
12.
Large nuclei
✎
collect
13.
Low eccentricity cells
✎
collect
14.
Metaphase cells
✎
collect
15.
Other phenotype
✎
collect
16.
Proliferating cells
✎
collect
17.
SM phenotype (abundance of large cells with protrusions and bright nuclei)
✎
collect
18.
Small cells
✎
collect
EMBL-secretion screen
(E1_SyM_1)
Primary
1.
Mild inhibition of secretion
✎
collect
2.
Strong inhibition of secretion
✎
collect
EMBL-secretion screen
(E1_SyM_2)
Primary
1.
Enhanced secretion
✎
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GFP-RNF168
(G1_SyM_1)
Primary
1.
Accumulation of GFP-RNF168 on nuclear bodies
✎
collect
JCB Metazoan actinome
(J1_SyM_1)
Primary
1.
Apoptotic DNA
✎
collect
2.
Cell shape bipolar or elongated
✎
collect
3.
Cell shape geometric
✎
collect
4.
Cell shape processes or spiky or stretchy
✎
collect
5.
Cell shape round or non-adherent
✎
collect
6.
Cell shape variable
✎
collect
7.
Decreased DNA area
✎
collect
8.
Decreased cell number
✎
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9.
Decreased cell size
✎
collect
10.
Decreased level of actin
✎
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11.
Decreased number of filopodia
✎
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12.
Decreased width of lamellae
✎
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13.
Disorganised peripheral actin
✎
collect
14.
Increased DNA area
✎
collect
15.
Increased actin over nucleus
✎
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16.
Increased cell number
✎
collect
17.
Increased cell size
✎
collect
18.
Increased cytoplasmic actin
✎
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19.
Increased level of actin
✎
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20.
Increased level of microtubules
✎
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21.
Increased mitotic index
✎
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22.
Increased number of actin puncta or dots
✎
collect
23.
Increased number of actin stress fibres
✎
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24.
Increased number of cortical actin stress fibres
✎
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25.
Increased number of filopodia
✎
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26.
Increased number of multinucleate cells
✎
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27.
Increased number of transverse actin stress fibres
✎
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28.
Increased number of zigzag actin stress fibres
✎
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29.
Increased peripheral actin
✎
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30.
Increased width of lamellae
✎
collect
31.
Loss of cell monolayer
✎
collect
32.
Microtubule clumps
✎
collect
33.
Microtubule nuclear bracket
✎
collect
34.
Microtubule nuclear ring
✎
collect
35.
Microtubule processes
✎
collect
36.
Microtubules disorganised
✎
collect
37.
Misshapen DNA
✎
collect
38.
Motile lamellae
✎
collect
39.
Nuclear actin ring
✎
collect
40.
Variable cell size
✎
collect
Mitocheck
(M1_SyM_1)
Primary
1.
Binuclear
✎
collect
2.
Cell death
✎
collect
3.
Dynamic changes
✎
collect
4.
Grape
✎
collect
5.
Increased proliferation
✎
collect
6.
Large
✎
collect
7.
Mitotic delay
✎
collect
8.
Polylobed
✎
collect
Mitocheck
(M1_SyM_2)
Validation
1.
Cell death
✎
collect
2.
Cell migration
✎
collect
3.
Large nucleus
✎
collect
4.
Metaphase alignment problem
✎
collect
5.
Metaphase arrest/delay
✎
collect
6.
Nuclei stay together
✎
collect
7.
Reduced mitotic index
✎
collect
8.
Segregation problem
✎
collect
9.
Small nucleus
✎
collect
10.
Strange nuclear shape
✎
collect
NF-kB oscillation screen
(N1_SyM_1)
Primary
1.
Decreased oscillation
✎
collect
2.
Different oscillation pattern
✎
collect
3.
Increased oscillation
✎
collect
4.
No oscillation
✎
collect
PP2A-B55α
(P1_SyM_1)
Primary
1.
Normal mitotic exit
✎
collect
2.
Prolonged mitotic exit
✎
collect
Phagokinetic track
(P2_SyM_1)
Primary
1.
Impaired cell migration with increased protrusive activity
✎
collect
2.
Impaired cell migration
✎
collect
3.
Increased cell migration and increased cell area
✎
collect
4.
Increased directional cell migration
✎
collect