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CHEBI:7477 - naproxen sodium
| Formula | C14H13O3.Na |
| Net Charge | 0 |
| Average Mass | 252.245 |
| Monoisotopic Mass | 252.07624 |
| SMILES | COc1ccc2cc([C@H](C)C(=O)[O-])ccc2c1.[Na+] |
| InChI | InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1 |
| InChIKey | CDBRNDSHEYLDJV-FVGYRXGTSA-M |
| Roles Classification |
|---|
| Biological Roles: | cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. |
| Applications: | anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. antirheumatic drug A drug used to treat rheumatoid arthritis. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. anti-inflammatory agent Any compound that has anti-inflammatory effects. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| naproxen sodium (CHEBI:7477) has part naproxen(1−) (CHEBI:59527) |
| naproxen sodium (CHEBI:7477) has role analgesic (CHEBI:35480) |
| naproxen sodium (CHEBI:7477) has role anti-inflammatory agent (CHEBI:67079) |
| naproxen sodium (CHEBI:7477) has role anti-ulcer drug (CHEBI:49201) |
| naproxen sodium (CHEBI:7477) has role antipyretic (CHEBI:35493) |
| naproxen sodium (CHEBI:7477) has role antirheumatic drug (CHEBI:35842) |
| naproxen sodium (CHEBI:7477) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| naproxen sodium (CHEBI:7477) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| naproxen sodium (CHEBI:7477) has role gout suppressant (CHEBI:35845) |
| naproxen sodium (CHEBI:7477) has role non-narcotic analgesic (CHEBI:35481) |
| naproxen sodium (CHEBI:7477) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| naproxen sodium (CHEBI:7477) is a organic sodium salt (CHEBI:38700) |
| IUPAC Name |
|---|
| sodium (2S)-2-(6-methoxy-2-naphthyl)propanoate |
| Synonyms | Source |
|---|---|
| BAY-117031 | ChEMBL |
| BAY117031 | ChEMBL |
| BAYH6689 | ChEMBL |
| Naproxen sodium anhydrous | ChEMBL |
| Naproxen sodium salt | ChEMBL |
| RS-3650 | ChEMBL |
| Brand Names | Source |
|---|---|
| Anaprox | ChEMBL |
| Anaprox ds | ChEMBL |
| Naprelan | ChEMBL |
| Naproxen sodium component of aleve-d | ChEMBL |
| Naproxen sodium component of treximet | ChEMBL |
| Synflex | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:6378035 | Beilstein |
| CAS:26159-34-2 | ChemIDplus |
| Citations |
|---|