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CHEBI:7477 - naproxen sodium
| Formula | C14H13O3.Na |
| Net Charge | 0 |
| Average Mass | 252.245 |
| Monoisotopic Mass | 252.07624 |
| SMILES | COc1ccc2cc([C@H](C)C(=O)[O-])ccc2c1.[Na+] |
| InChI | InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1 |
| InChIKey | CDBRNDSHEYLDJV-FVGYRXGTSA-M |
| Roles Classification |
|---|
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. anti-inflammatory agent Any compound that has anti-inflammatory effects. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. antirheumatic drug A drug used to treat rheumatoid arthritis. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| naproxen sodium (CHEBI:7477) has part naproxen(1−) (CHEBI:59527) |
| naproxen sodium (CHEBI:7477) has role analgesic (CHEBI:35480) |
| naproxen sodium (CHEBI:7477) has role anti-inflammatory agent (CHEBI:67079) |
| naproxen sodium (CHEBI:7477) has role anti-ulcer drug (CHEBI:49201) |
| naproxen sodium (CHEBI:7477) has role antipyretic (CHEBI:35493) |
| naproxen sodium (CHEBI:7477) has role antirheumatic drug (CHEBI:35842) |
| naproxen sodium (CHEBI:7477) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| naproxen sodium (CHEBI:7477) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| naproxen sodium (CHEBI:7477) has role gout suppressant (CHEBI:35845) |
| naproxen sodium (CHEBI:7477) has role non-narcotic analgesic (CHEBI:35481) |
| naproxen sodium (CHEBI:7477) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| naproxen sodium (CHEBI:7477) is a naphthalenes (CHEBI:25477) |
| naproxen sodium (CHEBI:7477) is a organic molecular entity (CHEBI:50860) |
| naproxen sodium (CHEBI:7477) is a organic sodium salt (CHEBI:38700) |
| IUPAC Name |
|---|
| sodium (2S)-2-(6-methoxy-2-naphthyl)propanoate |
| Synonyms | Source |
|---|---|
| BAY-117031 | ChEMBL |
| BAY117031 | ChEMBL |
| BAYH6689 | ChEMBL |
| Naproxen sodium anhydrous | ChEMBL |
| Naproxen sodium salt | ChEMBL |
| RS-3650 | ChEMBL |
| Brand Names | Source |
|---|---|
| Anaprox | ChEMBL |
| Anaprox ds | ChEMBL |
| Naprelan | ChEMBL |
| Naproxen sodium component of aleve-d | ChEMBL |
| Naproxen sodium component of treximet | ChEMBL |
| Synflex | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:6378035 | Beilstein |
| CAS:26159-34-2 | ChemIDplus |
| Citations |
|---|