EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:90876 - Lonsurf
| ChEBI ID | CHEBI:90876 |
| ChEBI Name | Lonsurf |
| Stars | |
| Definition | A mixture composed of trifluridine, a nucleoside metabolic inhibitor, and tipiracil hydrochloride, a thymidine phosphorylase inhibitor. Lonsurf is used for treatment of advanced/relapsed unresectable colorectal cancer. |
| Last Modified | 8 January 2016 |
| Submitter | Steve |
| Roles Classification |
|---|
| Biological Role: | antifolate An antimetabolite that impairs the action of folic acids |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Lonsurf (CHEBI:90876) has part tipiracil hydrochloride (CHEBI:90877) |
| Lonsurf (CHEBI:90876) has part trifluridine (CHEBI:75179) |
| Lonsurf (CHEBI:90876) has role antifolate (CHEBI:73913) |
| Lonsurf (CHEBI:90876) has role antineoplastic agent (CHEBI:35610) |
| Lonsurf (CHEBI:90876) is a mixture (CHEBI:60004) |
| Synonyms | Source |
|---|---|
| Trifluridine - tipiracil hydrochloride mixt | KEGG DRUG |
| TAS-102 | ChEBI |
| Brand Name | Source |
|---|---|
| Lonsurf | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D10526 | KEGG DRUG |
| Citations |
|---|