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CHEBI:84743 - amiloride hydrochloride

ChEBI IDCHEBI:84743
ChEBI Nameamiloride hydrochloride
Stars
DefinitionA hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.
Last Modified11 February 2015
SubmitterSteve
DownloadsMolfile
FormulaC6H8ClN7O.HCl
Net Charge0
Average Mass266.092
Monoisotopic Mass265.02456
SMILESCl.N=C(N)NC(=O)c1nc(Cl)c(N)nc1N
InChIInChI=1S/C6H8ClN7O.ClH/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h(H4,8,9,13)(H4,10,11,14,15);1H
InChIKeyACHKKGDWZVCSNH-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Application:
diuretic  An agent that promotes the excretion of urine through its effects on kidney function.
ChEBI Ontology
Outgoing Relation(s)
amiloride hydrochloride (CHEBI:84743) has part amiloride(1+) (CHEBI:84745)
amiloride hydrochloride (CHEBI:84743) has role diuretic (CHEBI:35498)
amiloride hydrochloride (CHEBI:84743) has role sodium channel blocker (CHEBI:38633)
amiloride hydrochloride (CHEBI:84743) is a hydrochloride (CHEBI:36807)
Incoming Relation(s)
amiloride hydrochloride dihydrate (CHEBI:2640) has part amiloride hydrochloride (CHEBI:84743)
IUPAC Name 
3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride
Synonyms  Source
amiloride monohydrochlorideChEBI
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochlorideChemIDplus
Amiloride HClChemIDplus
Amiloride hydrochloride anhydrousChemIDplus
Amiloride chlorideChemIDplus
Manual XrefsDatabases
DB00594DrugBank
AmilorideWikipedia
Registry NumbersSources
Reaxys:4038903Reaxys
CAS:2016-88-8ChemIDplus
Citations