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CHEBI:2640 - amiloride hydrochloride dihydrate

ChEBI IDCHEBI:2640
ChEBI Nameamiloride hydrochloride dihydrate
Stars
DefinitionA hydrate that is the dihydrate of amiloride hydrochloride.
Last Modified11 February 2015
DownloadsMolfile
FormulaC6H8ClN7O.2H2O.HCl
Net Charge0
Average Mass302.122
Monoisotopic Mass301.04569
SMILESCl.N=C(N)NC(=O)c1nc(Cl)c(N)nc1N.O.O
InChIInChI=1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2
InChIKeyLTKVFMLMEYCWMK-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Application:
diuretic  An agent that promotes the excretion of urine through its effects on kidney function.
ChEBI Ontology
Outgoing Relation(s)
amiloride hydrochloride dihydrate (CHEBI:2640) has part amiloride hydrochloride (CHEBI:84743)
amiloride hydrochloride dihydrate (CHEBI:2640) has role diuretic (CHEBI:35498)
amiloride hydrochloride dihydrate (CHEBI:2640) has role sodium channel blocker (CHEBI:38633)
amiloride hydrochloride dihydrate (CHEBI:2640) is a hydrate (CHEBI:35505)
IUPAC Name 
N-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate
INN  Source
ModamideChemIDplus
Synonym  Source
Amilorid hydrochlorid-2-wasserChemIDplus
Manual XrefsDatabases
DB00594DrugBank
D00649KEGG DRUG
AmilorideWikipedia
Registry NumbersSources
Reaxys:13319490Reaxys
CAS:17440-83-4ChemIDplus