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CHEBI:8249 - piroxicam
| Formula | C15H13N3O4S |
| Net Charge | 0 |
| Average Mass | 331.353 |
| Monoisotopic Mass | 331.06268 |
| SMILES | CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |
| InChI | InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) |
| InChIKey | QYSPLQLAKJAUJT-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antirheumatic drug A drug used to treat rheumatoid arthritis. anti-inflammatory agent Any compound that has anti-inflammatory effects. vulnerary A drug used in treating and healing of wounds. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| piroxicam (CHEBI:8249) has role analgesic (CHEBI:35480) |
| piroxicam (CHEBI:8249) has role anti-inflammatory agent (CHEBI:67079) |
| piroxicam (CHEBI:8249) has role antirheumatic drug (CHEBI:35842) |
| piroxicam (CHEBI:8249) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| piroxicam (CHEBI:8249) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| piroxicam (CHEBI:8249) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| piroxicam (CHEBI:8249) has role ophthalmology drug (CHEBI:66981) |
| piroxicam (CHEBI:8249) has role vulnerary (CHEBI:73336) |
| piroxicam (CHEBI:8249) is a benzothiazine (CHEBI:46899) |
| piroxicam (CHEBI:8249) is a monocarboxylic acid amide (CHEBI:29347) |
| piroxicam (CHEBI:8249) is a pyridines (CHEBI:26421) |
| Incoming Relation(s) |
| ampiroxicam (CHEBI:31210) has functional parent piroxicam (CHEBI:8249) |
| droxicam (CHEBI:76133) has functional parent piroxicam (CHEBI:8249) |
| IUPAC Name |
|---|
| 4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide |
| INNs | Source |
|---|---|
| piroxicam | WHO MedNet |
| piroxicamum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid | ChemIDplus |
| CP-16,171 | ChEMBL |
| NSC-666076 | ChEMBL |
| Piroxicam | KEGG COMPOUND |
| Pyroxycam | ChemIDplus |
| Brand Names | Source |
|---|---|
| Brexidol | ChEMBL |
| Feldene | DrugBank |
| FELDENE | KEGG DRUG |
| Feldene 20 | ChEMBL |
| Feldene p | ChEMBL |
| Flamatrol | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:627692 | Reaxys |
| CAS:36322-90-4 | ChemIDplus |
| CAS:36322-90-4 | NIST Chemistry WebBook |
| Citations |
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