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CHEBI:76133 - droxicam
| Formula | C16H11N3O5S |
| Net Charge | 0 |
| Average Mass | 357.347 |
| Monoisotopic Mass | 357.04194 |
| SMILES | CN1c2c(oc(=O)n(-c3ccccn3)c2=O)-c2ccccc2S1(=O)=O |
| InChI | InChI=1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3 |
| InChIKey | OEHFRZLKGRKFAS-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. hepatotoxic agent A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. platelet aggregation inhibitor A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| droxicam (CHEBI:76133) has functional parent piroxicam (CHEBI:8249) |
| droxicam (CHEBI:76133) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| droxicam (CHEBI:76133) has role hepatotoxic agent (CHEBI:50908) |
| droxicam (CHEBI:76133) has role non-narcotic analgesic (CHEBI:35481) |
| droxicam (CHEBI:76133) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| droxicam (CHEBI:76133) has role platelet aggregation inhibitor (CHEBI:50427) |
| droxicam (CHEBI:76133) has role prodrug (CHEBI:50266) |
| droxicam (CHEBI:76133) is a organic heterotricyclic compound (CHEBI:26979) |
| droxicam (CHEBI:76133) is a pyridines (CHEBI:26421) |
| IUPAC Name |
|---|
| 5-methyl-3-(pyridin-2-yl)-2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide |
| INNs | Source |
|---|---|
| droxicam | KEGG DRUG |
| droxicamum | ChemIDplus |
| droxicam | WHO MedNet |
| droxicam | WHO MedNet |
| Citations |
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