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CHEBI:31210 - ampiroxicam
| Formula | C20H21N3O7S |
| Net Charge | 0 |
| Average Mass | 447.469 |
| Monoisotopic Mass | 447.11002 |
| SMILES | CCOC(=O)OC(C)OC1=C(C(=O)Nc2ccccn2)N(C)S(=O)(=O)c2ccccc21 |
| InChI | InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24) |
| InChIKey | LSNWBKACGXCGAJ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| ampiroxicam (CHEBI:31210) has functional parent piroxicam (CHEBI:8249) |
| ampiroxicam (CHEBI:31210) has role analgesic (CHEBI:35480) |
| ampiroxicam (CHEBI:31210) has role antirheumatic drug (CHEBI:35842) |
| ampiroxicam (CHEBI:31210) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| ampiroxicam (CHEBI:31210) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| ampiroxicam (CHEBI:31210) has role prodrug (CHEBI:50266) |
| ampiroxicam (CHEBI:31210) is a acetal (CHEBI:59769) |
| ampiroxicam (CHEBI:31210) is a aminopyridine (CHEBI:38207) |
| ampiroxicam (CHEBI:31210) is a benzothiazine (CHEBI:46899) |
| ampiroxicam (CHEBI:31210) is a etabonate ester (CHEBI:50850) |
| ampiroxicam (CHEBI:31210) is a monocarboxylic acid amide (CHEBI:29347) |
| ampiroxicam (CHEBI:31210) is a sulfonamide (CHEBI:35358) |
| IUPAC Name |
|---|
| ethyl 1-{[2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate |
| INNs | Source |
|---|---|
| ampiroxicam | ChemIDplus |
| ampiroxicam | WHO MedNet |
| ampiroxicam | WHO MedNet |
| ampiroxicamum | ChemIDplus |
| Synonyms | Source |
|---|---|
| carbonic acid ethyl 1-({2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl}oxy)ethyl ester S,S-dioxide | ChemIDplus |
| CP 65703 | ChemIDplus |
| CP-65703 | ChemIDplus |
| Brand Name | Source |
|---|---|
| Flucam | KEGG DRUG |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5184713 | Reaxys |
| CAS:99464-64-9 | KEGG DRUG |
| CAS:99464-64-9 | ChemIDplus |
| Citations |
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