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CHEBI:7640 - nortriptyline
| Formula | C19H21N |
| Net Charge | 0 |
| Average Mass | 263.384 |
| Monoisotopic Mass | 263.16740 |
| SMILES | CNCCC=C1c2ccccc2CCc2ccccc21 |
| InChI | InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3 |
| InChIKey | PHVGLTMQBUFIQQ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. |
| Applications: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| nortriptyline (CHEBI:7640) has functional parent amitriptyline (CHEBI:2666) |
| nortriptyline (CHEBI:7640) has parent hydride dibenzo[a,d][7]annulene (CHEBI:35642) |
| nortriptyline (CHEBI:7640) has role adrenergic uptake inhibitor (CHEBI:35640) |
| nortriptyline (CHEBI:7640) has role analgesic (CHEBI:35480) |
| nortriptyline (CHEBI:7640) has role antidepressant (CHEBI:35469) |
| nortriptyline (CHEBI:7640) has role antineoplastic agent (CHEBI:35610) |
| nortriptyline (CHEBI:7640) has role apoptosis inducer (CHEBI:68495) |
| nortriptyline (CHEBI:7640) has role drug metabolite (CHEBI:49103) |
| nortriptyline (CHEBI:7640) is a organic tricyclic compound (CHEBI:51959) |
| nortriptyline (CHEBI:7640) is a secondary amine (CHEBI:32863) |
| IUPAC Name |
|---|
| 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine |
| INNs | Source |
|---|---|
| nortriptyline | WHO MedNet |
| nortriptyline | WHO MedNet |
| nortriptylinum | WHO MedNet |
| nortriptylina | WHO MedNet |
| Synonyms | Source |
|---|---|
| Nortriptyline | KEGG COMPOUND |
| Avantyl | ChemIDplus |
| 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine | NIST Chemistry WebBook |
| demethylamitriptyline | ChemIDplus |
| desmethylamitriptyline | ChemIDplus |
| 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine | NIST Chemistry WebBook |
| Citations |
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