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CHEBI:76310 - (±)-menthol
| ChEBI ID | CHEBI:76310 |
| ChEBI Name | (±)-menthol |
| Stars | |
| ASCII Name | (+-)-menthol |
| Definition | A racemate comprising equimolar amounts of (+)- and (−)-menthol. Both (±)- and (−)-menthol are used to relieve symptoms of conditions such as bronchitis and sinusitis. When applied to the skin, menthol dilates the blood vessels, giving a sensation of coldness followed by an analgesic effect that relieves itching. It is therefore used in creams and ointments for the relief of pruritis and urticaria. |
| Last Modified | 19 November 2013 |
| Submitter | Gareth Owen |
| Roles Classification |
|---|
| Applications: | antipruritic drug A drug, usually applied topically, that relieves pruritus (itching). antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. vasodilator agent A drug used to cause dilation of the blood vessels. antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (±)-menthol (CHEBI:76310) has part (+)-menthol (CHEBI:76306) |
| (±)-menthol (CHEBI:76310) has part (−)-menthol (CHEBI:15409) |
| (±)-menthol (CHEBI:76310) has role antipruritic drug (CHEBI:59683) |
| (±)-menthol (CHEBI:76310) has role antispasmodic drug (CHEBI:53784) |
| (±)-menthol (CHEBI:76310) has role antitussive (CHEBI:51177) |
| (±)-menthol (CHEBI:76310) has role vasodilator agent (CHEBI:35620) |
| (±)-menthol (CHEBI:76310) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol |
| INNs | Source |
|---|---|
| racementhol | ChemIDplus |
| racementholum | ChemIDplus |
| racementol | ChemIDplus |
| racémenthol | WHO MedNet |
| Synonyms | Source |
|---|---|
| (+/-)-menthol | ChEBI |
| rac-menthol | ChemIDplus |
| DL-menthol | ChEBI |
| d,l-menthol | ChemIDplus |
| dl-menthol | KEGG DRUG |
| Citations |
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