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CHEBI:747353 - darolutamide
| ChEBI ID | CHEBI:747353 |
| ChEBI Name | darolutamide |
| Stars | |
| Definition | A diastereoisomeric mixture comprising equimolar amounts of (S,R)-darolutamide and (S,S)-darolutamide. It is an androgen receptor antagonist used for the treatment of non-metastatic castration-resistant prostate cancer. |
| Last Modified | 10 April 2026 |
| Formula | C19H19ClN6O2 |
| Net Charge | 0 |
| Average Mass | 398.854 |
| Monoisotopic Mass | 398.12580 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| darolutamide (CHEBI:747353) has part (S,R)-darolutamide (CHEBI:747483) |
| darolutamide (CHEBI:747353) has part (S,S)-darolutamide (CHEBI:747482) |
| darolutamide (CHEBI:747353) has role androgen antagonist (CHEBI:35497) |
| darolutamide (CHEBI:747353) has role antineoplastic agent (CHEBI:35610) |
| darolutamide (CHEBI:747353) has role teratogenic agent (CHEBI:50905) |
| darolutamide (CHEBI:747353) is a diastereoisomeric mixture (CHEBI:60915) |
| INNs | Source |
|---|---|
| darolutamida | WHO MedNet |
| darolutamide | WHO MedNet |
| darolutamide | WHO MedNet |
| darolutamidum | WHO MedNet |
| Synonyms | Source |
|---|---|
| BAY 1841788 | DrugBank |
| BAY-1841788 | DrugBank |
| BAY1841788 | DrugBank |
| N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide | CAS |
| N-{(2S)-1-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide | ChEBI |
| ODM 201 | DrugBank |
| Brand Name | Source |
|---|---|
| Nubeqa | DrugBank |
| Manual Xrefs | Databases |
|---|---|
| 38772320 | ChemSpider |
| Darolutamide | Wikipedia |
| DB12941 | DrugBank |
| Registry Numbers | Sources |
|---|---|
| CAS:1297538-32-9 | CAS |
| Citations |
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