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CHEBI:73038 - parecoxib
| Formula | C19H18N2O4S |
| Net Charge | 0 |
| Average Mass | 370.430 |
| Monoisotopic Mass | 370.09873 |
| SMILES | CCC(=O)NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1 |
| InChI | InChI=1S/C19H18N2O4S/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15/h4-12H,3H2,1-2H3,(H,21,22) |
| InChIKey | TZRHLKRLEZJVIJ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| parecoxib (CHEBI:73038) has functional parent valdecoxib (CHEBI:63634) |
| parecoxib (CHEBI:73038) has role analgesic (CHEBI:35480) |
| parecoxib (CHEBI:73038) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| parecoxib (CHEBI:73038) has role non-narcotic analgesic (CHEBI:35481) |
| parecoxib (CHEBI:73038) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| parecoxib (CHEBI:73038) has role prodrug (CHEBI:50266) |
| parecoxib (CHEBI:73038) is a N-sulfonylcarboxamide (CHEBI:90852) |
| parecoxib (CHEBI:73038) is a isoxazoles (CHEBI:55373) |
| IUPAC Name |
|---|
| N-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl}propanamide |
| INNs | Source |
|---|---|
| parecoxib | WHO MedNet |
| parecoxib | WHO MedNet |
| parécoxib | WHO MedNet |
| parecoxibum | WHO MedNet |
| Synonyms | Source |
|---|---|
| N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide | ChemIDplus |
| Rayzon | ChEMBL |
| SC 69124 | ChemIDplus |
| SC-69124 | ChemIDplus |
| Citations |
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