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CHEBI:64122 - (R)-(+)-sulpiride

Default Structure
ChEBI IDCHEBI:64122
ChEBI Name(R)-(+)-sulpiride
Stars
ASCII Name(R)-(+)-sulpiride
DefinitionAn optically active form of sulpiride having (R)-configuration. The active enantiomer of the racemic drug sulpiride.
Last Modified7 March 2012
SubmitterSteve
DownloadsMolfile
FormulaC15H23N3O4S
Net Charge0
Average Mass341.433
Monoisotopic Mass341.14093
SMILESCCN1CCC[C@@H]1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC
InChIInChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1
InChIKeyBGRJTUBHPOOWDU-LLVKDONJSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
antiemetic  A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
(R)-(+)-sulpiride (CHEBI:64122) is a sulpiride (CHEBI:32168)
(R)-(+)-sulpiride (CHEBI:64122) is enantiomer of (S)-(−)-sulpiride (CHEBI:64119)
Incoming Relation(s)
(S)-(−)-sulpiride (CHEBI:64119) is enantiomer of (R)-(+)-sulpiride (CHEBI:64122)
Synonyms  Source
(R)-(+)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamideChEBI
(R)-(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamideChEBI
(R)-sulpirideChEBI
(+)-sulpirideChEBI
Registry NumbersSources
Reaxys:4298776Reaxys
CAS:23756-79-8ChemIDplus