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CHEBI:32168 - sulpiride

ChEBI IDCHEBI:32168
ChEBI Namesulpiride
Stars
DefinitionA member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Last Modified22 February 2017
DownloadsMolfile
FormulaC15H23N3O4S
Net Charge0
Average Mass341.433
Monoisotopic Mass341.14093
SMILESCCN1CCCC1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC
InChIInChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)
InChIKeyBGRJTUBHPOOWDU-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
antiemetic  A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
sulpiride (CHEBI:32168) has role antidepressant (CHEBI:35469)
sulpiride (CHEBI:32168) has role antiemetic (CHEBI:50919)
sulpiride (CHEBI:32168) has role antipsychotic agent (CHEBI:35476)
sulpiride (CHEBI:32168) has role dopaminergic antagonist (CHEBI:48561)
sulpiride (CHEBI:32168) is a N-alkylpyrrolidine (CHEBI:46775)
sulpiride (CHEBI:32168) is a benzamides (CHEBI:22702)
sulpiride (CHEBI:32168) is a sulfonamide (CHEBI:35358)
Incoming Relation(s)
(R)-(+)-sulpiride (CHEBI:64122) is a sulpiride (CHEBI:32168)
(S)-(−)-sulpiride (CHEBI:64119) is a sulpiride (CHEBI:32168)
IUPAC Name 
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
INNs  Source
sulpiridaDrugBank
sulpirideKEGG DRUG
sulpiridumDrugBank
Synonyms  Source
5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamideChemIDplus
N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamideChemIDplus
N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamideChemIDplus
SulpiridDrugBank
(±)-sulpirideNIST Chemistry WebBook
SulpyridDrugBank
Manual XrefsDatabases
2537DrugCentral
D01226KEGG DRUG
DB00391DrugBank
DE2903891Patent
LSM-5080LINCS
SulpirideWikipedia
US3342826Patent
Registry NumbersSources
Reaxys:494008Reaxys
CAS:15676-16-1NIST Chemistry WebBook
CAS:15676-16-1KEGG DRUG
CAS:15676-16-1ChemIDplus
Citations