tenofovir (anhydrous) (CHEBI:63625)

CHEBI:63625 - tenofovir (anhydrous)

ChEBI ID	CHEBI:63625
ChEBI Name	tenofovir (anhydrous)
Stars
Definition	A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
Last Modified	19 June 2017
Downloads	Molfile

Formula	C9H14N5O4P
Net Charge	0
Average Mass	287.216
Monoisotopic Mass	287.07834
SMILES	C[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O
InChI	InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
InChIKey	SGOIRFVFHAKUTI-ZCFIWIBFSA-N

Wikipedia

Roles Classification

anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus.

HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase.

antiviral agent A substance that destroys or inhibits replication of viruses.

anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

ChEBI Ontology

Outgoing Relation(s)
	tenofovir (anhydrous) (CHEBI:63625) has role anti-HBV agent (CHEBI:64951)
	tenofovir (anhydrous) (CHEBI:63625) has role anti-HIV agent (CHEBI:64946)
	tenofovir (anhydrous) (CHEBI:63625) has role antiinfective agent (CHEBI:35441)
	tenofovir (anhydrous) (CHEBI:63625) has role antineoplastic agent (CHEBI:35610)
	tenofovir (anhydrous) (CHEBI:63625) has role antiviral agent (CHEBI:22587)
	tenofovir (anhydrous) (CHEBI:63625) has role antiviral drug (CHEBI:36044)
	tenofovir (anhydrous) (CHEBI:63625) has role drug metabolite (CHEBI:49103)
	tenofovir (anhydrous) (CHEBI:63625) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756)
	tenofovir (anhydrous) (CHEBI:63625) is a nucleoside analogue (CHEBI:60783)
	tenofovir (anhydrous) (CHEBI:63625) is a organic molecular entity (CHEBI:50860)
	tenofovir (anhydrous) (CHEBI:63625) is a phosphonic acids (CHEBI:26069)
	tenofovir (anhydrous) (CHEBI:63625) is a purines (CHEBI:26401)
	tenofovir (anhydrous) (CHEBI:63625) is conjugate acid of tenofovir(1−) (CHEBI:134504)
Incoming Relation(s)
	tenofovir disoproxil (CHEBI:63717) has functional parent tenofovir (anhydrous) (CHEBI:63625)
	tenofovir hydrate (CHEBI:63716) has part tenofovir (anhydrous) (CHEBI:63625)
	tenofovir(1−) (CHEBI:134504) is conjugate base of tenofovir (anhydrous) (CHEBI:63625)

IUPAC Name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

INN	Source
tenofovir	ChemIDplus

Registry Numbers	Sources
Reaxys:7415378	Reaxys
CAS:147127-20-6	ChemIDplus

Citations