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CHEBI:134504 - tenofovir(1−)

ChEBI IDCHEBI:134504
ChEBI Nametenofovir(1−)
Stars
ASCII Nametenofovir(1-)
DefinitionA phosphorus oxoanion resulting from the removal of one proton from the phosphonic acid group of tenofovir. The major microspecies at pH 7.3.
Last Modified12 April 2017
SubmitterAnne Morgat
DownloadsMolfile
FormulaC9H13N5O4P
Net Charge-1
Average Mass286.208
Monoisotopic Mass286.07106
SMILESC[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)([O-])O
InChIInChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/p-1/t6-/m1/s1
InChIKeySGOIRFVFHAKUTI-ZCFIWIBFSA-M
Roles Classification
Biological Roles:
HIV-1 reverse transcriptase inhibitor  An entity which inhibits the activity of HIV-1 reverse transcriptase.
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
Application:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
ChEBI Ontology
Outgoing Relation(s)
tenofovir(1−) (CHEBI:134504) has role antiviral drug (CHEBI:36044)
tenofovir(1−) (CHEBI:134504) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756)
tenofovir(1−) (CHEBI:134504) is a phosphorus oxoanion (CHEBI:33461)
tenofovir(1−) (CHEBI:134504) is conjugate base of tenofovir (anhydrous) (CHEBI:63625)
Incoming Relation(s)
tenofovir (anhydrous) (CHEBI:63625) is conjugate acid of tenofovir(1−) (CHEBI:134504)
IUPAC Name 
hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
Synonym  Source
tenofovir (1−)ChEBI
UniProt Name  Source
tenofovirUniProt
Citations