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CHEBI:60902 - orphenadrine hydrochloride
| Formula | C18H24NO.Cl |
| Net Charge | 0 |
| Average Mass | 305.849 |
| Monoisotopic Mass | 305.15464 |
| SMILES | Cc1ccccc1C(OCC[NH+](C)C)c1ccccc1.[Cl-] |
| InChI | InChI=1S/C18H23NO.ClH/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;/h4-12,18H,13-14H2,1-3H3;1H |
| InChIKey | UQZKYYIKWZOKKD-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. |
| Applications: | muscle relaxant A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis. parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. antiparkinson drug A drug used in the treatment of Parkinson's disease. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| orphenadrine hydrochloride (CHEBI:60902) has part orphenadrine (CHEBI:7789) |
| orphenadrine hydrochloride (CHEBI:60902) has role antiparkinson drug (CHEBI:48407) |
| orphenadrine hydrochloride (CHEBI:60902) has role H1-receptor antagonist (CHEBI:37955) |
| orphenadrine hydrochloride (CHEBI:60902) has role muscarinic antagonist (CHEBI:48876) |
| orphenadrine hydrochloride (CHEBI:60902) has role muscle relaxant (CHEBI:51371) |
| orphenadrine hydrochloride (CHEBI:60902) has role NMDA receptor antagonist (CHEBI:60643) |
| orphenadrine hydrochloride (CHEBI:60902) has role parasympatholytic (CHEBI:50370) |
| orphenadrine hydrochloride (CHEBI:60902) is a hydrochloride (CHEBI:36807) |
| IUPAC Names |
|---|
| N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine hydrochloride |
| N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanaminium chloride |
| Synonyms | Source |
|---|---|
| 2-dimethylaminoethyl 2-methylbenzhydryl ether hydrochloride | ChemIDplus |
| mefenamin hydrochloride | ChemIDplus |
| N,N-dimethyl-2-(o-methyl-alpha-phenylbenzyloxy)ethylamine hydrochloride | ChemIDplus |
| Brand Name | Source |
|---|---|
| Disipal | KEGG DRUG |