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CHEBI:59540 - (+)-rolipram

ChEBI IDCHEBI:59540
ChEBI Name(+)-rolipram
Stars
DefinitionThe (S)-enantiomer of rolipram.
Last Modified25 February 2016
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC16H21NO3
Net Charge0
Average Mass275.348
Monoisotopic Mass275.15214
SMILES[H][C@]1(c2ccc(OC)c(OC3CCCC3)c2)CNC(=O)C1
InChIInChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m1/s1
InChIKeyHJORMJIFDVBMOB-GFCCVEGCSA-N
Roles Classification
Biological Role:
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor  An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
Application:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
(+)-rolipram (CHEBI:59540) is a rolipram (CHEBI:104872)
(+)-rolipram (CHEBI:59540) is enantiomer of (−)-rolipram (CHEBI:40133)
Incoming Relation(s)
(−)-rolipram (CHEBI:40133) is enantiomer of (+)-rolipram (CHEBI:59540)
IUPAC Name 
(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Synonym  Source
(S)-(+)-rolipramChEBI
Manual XrefsDatabases
LSM-25607LINCS
Registry NumbersSources
CAS:85416-73-5ChemIDplus