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CHEBI:40133 - (−)-rolipram

ChEBI IDCHEBI:40133
ChEBI Name(−)-rolipram
Stars
ASCII Name(-)-rolipram
DefinitionThe (R)-enantiomer of rolipram.
Secondary ChEBI IDsCHEBI:40062, CHEBI:40127, CHEBI:45436, CHEBI:281755
Last Modified16 August 2017
DownloadsMolfile
FormulaC16H21NO3
Net Charge0
Average Mass275.348
Monoisotopic Mass275.15214
SMILES[H][C@@]1(c2ccc(OC)c(OC3CCCC3)c2)CNC(=O)C1
InChIInChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m0/s1
InChIKeyHJORMJIFDVBMOB-LBPRGKRZSA-N
Roles Classification
Biological Role:
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor  An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
Application:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
(−)-rolipram (CHEBI:40133) is a rolipram (CHEBI:104872)
(−)-rolipram (CHEBI:40133) is enantiomer of (+)-rolipram (CHEBI:59540)
Incoming Relation(s)
(+)-rolipram (CHEBI:59540) is enantiomer of (−)-rolipram (CHEBI:40133)
IUPAC Name 
(4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Synonyms  Source
ROLIPRAMPDBeChem
(R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-oneChEMBL
(R)-(−)-rolipramChEBI
(R)-rolipramChEBI
Manual XrefsDatabases
ROLPDBeChem
LSM-25638LINCS
Registry NumbersSources
Beilstein:5442919Beilstein