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CHEBI:59269 - dexbrompheniramine

ChEBI IDCHEBI:59269
ChEBI Namedexbrompheniramine
Stars
DefinitionThe (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Last Modified22 February 2017
SubmitterGareth Owen
DownloadsMolfile
FormulaC16H19BrN2
Net Charge0
Average Mass319.246
Monoisotopic Mass318.07316
SMILESCN(C)CC[C@@H](c1ccc(Br)cc1)c1ccccn1
InChIInChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1
InChIKeyZDIGNSYAACHWNL-HNNXBMFYSA-N
Wikipedia
Roles Classification
Biological Roles:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Applications:
anti-allergic agent  A drug used to treat allergic reactions.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
anti-allergic agent  A drug used to treat allergic reactions.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
ChEBI Ontology
Outgoing Relation(s)
dexbrompheniramine (CHEBI:59269) has role anti-allergic agent (CHEBI:50857)
dexbrompheniramine (CHEBI:59269) has role H1-receptor antagonist (CHEBI:37955)
dexbrompheniramine (CHEBI:59269) is a brompheniramine (CHEBI:3183)
Incoming Relation(s)
dexbrompheniramine maleate (CHEBI:59273) has part dexbrompheniramine (CHEBI:59269)
IUPAC Name 
(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine
INNs  Source
dexbrompheniramineChemIDplus
dexbromfeniraminaChemIDplus
dexbrompheniraminumChemIDplus
Synonyms  Source
d-brompheniramineChemIDplus
(+)-brompheniraminumChEBI
(S)-brompheniramineChEBI
(S)-(+)-brompheniramineChEBI
Manual XrefsDatabases
DB00405DrugBank
US3061517Patent
DexbrompheniramineWikipedia
LSM-5386LINCS
830DrugCentral
Registry NumbersSources
Beilstein:9398916Beilstein
CAS:132-21-8ChemIDplus
CAS:132-21-8NIST Chemistry WebBook