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CHEBI:3183 - brompheniramine

ChEBI IDCHEBI:3183
ChEBI Namebrompheniramine
Stars
DefinitionPheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Secondary ChEBI IDCHEBI:154051
Last Modified22 February 2017
DownloadsMolfile
FormulaC16H19BrN2
Net Charge0
Average Mass319.246
Monoisotopic Mass318.07316
SMILESCN(C)CCC(c1ccc(Br)cc1)c1ccccn1
InChIInChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
InChIKeyZDIGNSYAACHWNL-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Applications:
anti-allergic agent  A drug used to treat allergic reactions.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
ChEBI Ontology
Outgoing Relation(s)
brompheniramine (CHEBI:3183) has role anti-allergic agent (CHEBI:50857)
brompheniramine (CHEBI:3183) has role H1-receptor antagonist (CHEBI:37955)
brompheniramine (CHEBI:3183) is a organobromine compound (CHEBI:37141)
brompheniramine (CHEBI:3183) is a pyridines (CHEBI:26421)
Incoming Relation(s)
brompheniramine maleate (CHEBI:3184) has part brompheniramine (CHEBI:3183)
dexbrompheniramine (CHEBI:59269) is a brompheniramine (CHEBI:3183)
IUPAC Name 
3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine
INNs  Source
brompheniramineChemIDplus
bromfeniraminaChemIDplus
brompheniraminumChemIDplus
Synonyms  Source
BrompheniramineKEGG COMPOUND
[3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amineChEMBL
1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropaneChemIDplus
2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridineChemIDplus
3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamineNIST Chemistry WebBook
3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamineChemIDplus
Manual XrefsDatabases
C06857KEGG COMPOUND
D07543KEGG DRUG
DB00835DrugBank
US2567245Patent
US2676964Patent
BrompheniramineWikipedia
LSM-1736LINCS
408DrugCentral
Registry NumbersSources
Beilstein:217066Beilstein
CAS:86-22-6KEGG COMPOUND
CAS:86-22-6ChemIDplus
CAS:86-22-6NIST Chemistry WebBook
Citations