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CHEBI:53760 - eszopiclone

Default Structure
ChEBI IDCHEBI:53760
ChEBI Nameeszopiclone
Stars
DefinitionThe (5S)- (active) enantiomer of zopiclone. Unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia, eszopiclone is approved by the U.S. Food and Drug Administration for long-term use.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC17H17ClN6O3
Net Charge0
Average Mass388.815
Monoisotopic Mass388.10507
SMILESCN1CCN(C(=O)O[C@H]2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1
InChIInChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChIKeyGBBSUAFBMRNDJC-INIZCTEOSA-N
Wikipedia
Roles Classification
Applications:
central nervous system depressant  A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
central nervous system depressant  A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
ChEBI Ontology
Outgoing Relation(s)
eszopiclone (CHEBI:53760) has role anxiolytic drug (CHEBI:35474)
eszopiclone (CHEBI:53760) has role central nervous system depressant (CHEBI:35488)
eszopiclone (CHEBI:53760) has role sedative (CHEBI:35717)
eszopiclone (CHEBI:53760) is a zopiclone (CHEBI:32315)
eszopiclone (CHEBI:53760) is enantiomer of (5R)-zopiclone (CHEBI:53762)
Incoming Relation(s)
(5R)-zopiclone (CHEBI:53762) is enantiomer of eszopiclone (CHEBI:53760)
IUPAC Name 
(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
INNs  Source
eszopiclonaWHO MedNet
eszopicloneKEGG DRUG
Synonyms  Source
(+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylateChemIDplus
EsopicloneDrugBank
EstorraChEMBL
EszopiclonChEMBL
Eszopiclone civChEMBL
GSK-1755165ChEMBL
Manual XrefsDatabases
1068DrugCentral
D02624KEGG DRUG
DB00402DrugBank
EszopicloneWikipedia
Registry NumbersSources
Beilstein:8794636Beilstein
CAS:138729-47-2ChemIDplus
CAS:138729-47-2KEGG DRUG
Citations