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CHEBI:520819 - flufenamate
| Formula | C14H9F3NO2 |
| Net Charge | -1 |
| Average Mass | 280.225 |
| Monoisotopic Mass | 280.05909 |
| SMILES | O=C([O-])c1ccccc1Nc1cccc(C(F)(F)F)c1 |
| InChI | InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)/p-1 |
| InChIKey | LPEPZBJOKDYZAD-UHFFFAOYSA-M |
| Roles Classification |
|---|
| Biological Role: | non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| flufenamate (CHEBI:520819) has functional parent (trifluoromethyl)benzene (CHEBI:36810) |
| flufenamate (CHEBI:520819) has functional parent anthranilic acid (CHEBI:30754) |
| flufenamate (CHEBI:520819) has functional parent diphenylamine (CHEBI:4640) |
| flufenamate (CHEBI:520819) has role antipyretic (CHEBI:35493) |
| flufenamate (CHEBI:520819) has role non-narcotic analgesic (CHEBI:35481) |
| flufenamate (CHEBI:520819) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| flufenamate (CHEBI:520819) is a aromatic amino-acid anion (CHEBI:63473) |
| flufenamate (CHEBI:520819) is a monocarboxylic acid anion (CHEBI:35757) |
| flufenamate (CHEBI:520819) is conjugate base of flufenamic acid (CHEBI:42638) |
| Incoming Relation(s) |
| flufenamic acid (CHEBI:42638) is conjugate acid of flufenamate (CHEBI:520819) |
| IUPAC Name |
|---|
| 2-{[3-(trifluoromethyl)phenyl]amino}benzoate |
| Synonym | Source |
|---|---|
| 2-(3-(trifluoromethyl)phenylamino)benzoate | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5981335 | Reaxys |
| Citations |
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